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SAB5700348

Sigma-Aldrich

Anti-Phospho-FAK-Y397 antibody produced in rabbit

Synonym(s):

FADK, FAK, FAK1, FRNK, PPP1R71, PTK2, p125FAK, pp125FAK

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.43

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

114
 119
 120
 39
 48
 63
 99

species reactivity

mouse, human, rat

concentration

0.99 mg/ml

technique(s)

western blot: 1:500-1:1000

UniProt accession no.

Q05397

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr397)

Gene Information

human ... PTK2(5747)

Related Categories

General description

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic phosphorylated peptide around Y397 of human FAK (NP_722560.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

新产品

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