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SAB5700345

Sigma-Aldrich

Anti-Phospho-STAT2-Y690 antibody produced in rabbit

Synonym(s):

IMD44, ISGF-3, P113, STAT113, STAT2

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

97

species reactivity

rat, mouse, human

concentration

0.21 mg/ml

technique(s)

western blot: 1:500-1:1000

UniProt accession no.

P52630

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pTyr690)

Gene Information

human ... STAT2(6773)

Related Categories

General description

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. Multiple transcript variants encoding different isoforms have been found for this gene.

Immunogen

A synthetic phosphorylated peptide around Y690 of human STAT2 (NP_005410.1).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

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WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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