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SAB5700013

Anti-NBN antibody produced in rabbit

Name: Anti-NBN antibody produced in rabbit
Brand: SIGMA

Synonym(s):

AT-V1, AT-V2, ATV, NBN, NBS, NBS1, P95, nibrin

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About This Item

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Citations:

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Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

species reactivity

human, mouse

concentration

0.96 mg/ml

technique(s)

western blot: 1:500-1:2000

UniProt accession no.

O60934

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... NBN(4683)

Description

General description

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 435-754 of human NBN (NP_002476.2).

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Preparation Note

Store at -20℃. Avoid freeze / thaw cycles.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c