SAB5300165
Monoclonal Anti-OVA antibody produced in mouse
clone 3G2E1D9, ascites fluid
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Synonym(s):
N/A
UNSPSC Code:
12352203
NACRES:
NA.41
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biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
3G2E1D9, monoclonal
technique(s)
direct ELISA: 1:10,000
western blot: 1:500-1:2,000
isotype
IgG1
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
Ovalbumin (323-339) is an egg white protein surrounded by B-cell epitopes, which are bound by specific IgE antibodies. In addition to this, it also contains CD4+ T cell epitopes.
Immunogen
Ovalbumin
Mouse monoclonal antibody raised against OVA
Mouse monoclonal antibody raised against OVA
Biochem/physiol Actions
Ovalbumin (OVA) peptide 323-339 mediates 25-35% of T-cell response to intact OVA in isolated BALB/c mouse. OVA 323-339 has been widely used to determine the characteristics of class II major histocompatibility complex (MHC)-peptide binding and T-cell activation. It is extensively used in allergy research.
Physical form
Ascitic fluid containing 0.03% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
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Ingrid S Zeelenberg et al.
Cancer research, 68(4), 1228-1235 (2008-02-19)
Expression of non-self antigens by tumors can induce activation of T cells in vivo, although this activation can lead to either immunity or tolerance. CD8+ T-cell activation can be direct (if the tumor expresses MHC class I molecules) or indirect
Comparison between ovalbumin and ovalbumin peptide 323-339 responses in allergic mice: humoral and cellular aspects.
Sun LZ
Scandinavian Journal of Immunology, 71(5), 329-335 (2010)
Tian-Yu Song et al.
Nature communications, 12(1), 7003-7003 (2021-12-03)
Cancer cells acquire genetic heterogeneity to escape from immune surveillance during tumor evolution, but a systematic approach to distinguish driver from passenger mutations is lacking. Here we investigate the impact of different immune pressure on tumor clonal dynamics and immune
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