SAB4701098
Monoclonal Anti-CD3-APC antibody produced in mouse
clone APA1/1
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Synonym(s):
CD3 epsilon chain, CD3epsilon, IMD18, T3E
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
mouse
conjugate
Allophycocyanin conjugate
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
APA1/1, monoclonal
form
buffered aqueous solution
concentration
0.1 mg/mL
technique(s)
flow cytometry: 1.5 μg/mL
accession no.
BC049847
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Gene Information
human ... CD3E(916)
Related Categories
General description
The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation.
Immunogen
Purified human CD3 proteins isolated from thymus
Physical form
Solution in phosphate buffered saline with 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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