Anti- Staphylococcal Enterotoxin B-Peroxidase antibody produced in rabbit

Staphylococcus aureus is a Gram positive bacterium, that cause diseases in human population including food poisoning and toxic shock syndrome.¹ S. aureus express several secreted virulence factors, such as various enzymes, cytotoxins, exotoxins, and exfoliative toxins.¹ Exotoxins include more than 20 serologically classified staphylococcal enterotoxins (SEs), the best characterize are the SEs A, B through V and toxic shock syndrome toxin-1 (TSST-1), these enterotoxins are similar in activity, sequence, structure and molecular weight (~25-30 kDa).¹

purified Enterotoxin B from Staphylococcus aureus

The antibody may be used in various immunochemical techniques including ELISA.

Anti- Staphylococcal Enterotoxin B- peroxidase antibody specifically recognizes Staphylococcal Enterotoxin B (SEB) and has no cross reactivity with Staphylococcal Enterotoxin A (SEA), Cholera Toxin or Pseudomonas Exotoxin A.

SEA and SEB are known as superantigens due to their ability to bind class II MHC molecules on antigen presenting cells and stimulate extensive T-cells activation followed by massive cytokine release leading to an acute toxic shock.^1-4

SE proteins have a significant resistance to heat and acid, it is also resistant to gastrointestinal proteases including pepsin, trypsin, rennin and papain. Thus, killing the S. aureus bacteria may not be sufficient to eliminate these superantigens risk from causing food poisoning.

Supplied as a lyophilized powder.

Store the lyophilized product at 2–8 °C. For extended storage after reconstitution, keep at –20 °C in working aliquots. Avoid repeated freeze-thaw cycles. For continuous use after reconstitution, keep at 2–8 °C for up to 1 month. Solutions at working dilution should be discarded if not used within 12 hours.

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.

Unless otherwise stated in our catalog  our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.