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Key Documents

Safety Information

SAB3300019

Sigma-Aldrich

Monoclonal Anti-CK19 antibody produced in mouse

clone 2F8, purified immunoglobulin, buffered aqueous glycerol solution

Synonym(s):

Anti-K19, Anti-K1CS, Anti-MGC15366

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About This Item

UNSPSC Code:
12352203

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

2F8, monoclonal

form

buffered aqueous glycerol solution

mol wt

antigen 43.9 kDa

species reactivity

human

technique(s)

indirect immunofluorescence: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_002276

UniProt accession no.

P08727

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... KRT19(3880)

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Immunogen

Recombinant fragment expressed in E. coli corresponding to amino acids 240-390 of human CK19

Target description

Keratin 19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins, which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis.

Physical form

Solution in phosphate buffered saline containing 1% bovine serum albumin, 50% glycerol, and 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
A01500019

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Hang-Lung Chang et al.
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With recorded under-performance of current standard therapeutic strategies as highlighted by high rates of post-treatment (resection or local ablation) recurrence, resistance to chemotherapy, poor overall survival, and an increasing global incidence, hepatocellular carcinoma (HCC) constitutes a medical challenge. Accumulating evidence

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