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Key Documents

Safety Information

SAB2108706

Sigma-Aldrich

Anti-REST

affinity isolated antibody

Synonym(s):

Anti- XBR, Anti-NRSF

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100 G
CN¥1,118.44

CN¥1,118.44

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100 G
CN¥1,118.44

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

CN¥1,118.44

Please contact Customer Service for Availability

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

122 kDa

species reactivity

human

concentration

0.5-1 mg/mL

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100

Quality Level

100

Quality Level

200

Quality Level

200

form

solid

form

crystalline

form

crystalline

form

powder or crystals

storage temp.

2-30°C

storage temp.

-

storage temp.

-

storage temp.

-

pH

7.5-9.2 (20 °C, 50 g/L in H2O)

pH

7.5-9.0 (20 °C, 5%)

pH

7.5-9.0 (20 °C, 5%)

pH

8.5-10.0 (25 °C, 3 M in H2O)

density

1.42 g/cm3 at 20 °C

density

-

density

-

density

-

Immunogen

Synthetic peptide directed towards the middle region of human REST

Biochem/physiol Actions

REST is a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis.This gene encodes a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described; however, their full length nature has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Sequence

Synthetic peptide located within the following region: PMLPPSAVEEREAVSKTALASPPATMAANESQEIDEDEGIHSHEGSDLSD

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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    Certificates of Analysis (COA)

    Lot/Batch Number
    QC2163

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