SAB1408042
Anti-LMAN2L antibody produced in mouse
purified immunoglobulin, buffered aqueous solution
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Synonym(s):
DKFZp564L2423, MGC11139, VIPL
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~39.7 kDa
species reactivity
human
technique(s)
western blot: 1 μg/mL
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... LMAN2L(81562)
General description
Lectin mannose binding 2-like (LMAN2L) is a high-mannose type I membrane glycoprotein which is part of the L-type lectin family. It is expressed in many tissues. The gene encoding this protein is localized on human chromosome 2q11.2. Mouse polyclonal antibody raised against a full-length human LMAN2L protein.
Immunogen
LMAN2L (NP_110432, 1 a.a. ~ 348 a.a) full-length human protein.
Sequence
MAATLGPLGSWQQWRRCLSARDGSRMLLLLLLLGSGQGPQQVGAGQTFEYLKREHSLSKPYQGVGTGSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRDWELQVHFKIHGQGKKNLHGDGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQQERVFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMDIDGKHEWRDCIEVPGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELTVERTPEEEKLHRDVFLPSVDNMKLPEMTAPLPPLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRFY
Sequence
MAATLGPLGSWQQWRRCLSARDGSRMLLLLLLLGSGQGPQQVGAGQTFEYLKREHSLSKPYQGVGTGSSSLWNLMGNAMVMTQYIRLTPDMQSKQGALWNRVPCFLRDWELQVHFKIHGQGKKNLHGDGLAIWYTKDRMQPGPVFGNMDKFVGLGVFVDTYPNEEKQQERVFPYISAMVNNGSLSYDHERDGRPTELGGCTAIVRNLHYDTFLVIRYVKRHLTIMMDIDGKHEWRDCIEVPGVRLPRGYYFGTSSITGDLSDNHDVISLKLFELTVERTPEEEKLHRDVFLPSVDNMKLPEMTAPLPPLSGLALFLIVFFSLVFSVFAIVIGIILYNKWQEQSRKRFY
Biochem/physiol Actions
Lectin mannose binding 2-like (LMAN2L) is a cargo receptor in the endoplasmic reticulum which has a role in glycoprotein transport. It may be involved in targeting folded glycoproteins to the Golgi and misfolded glycoproteins to the ubiquitin-proteasome pathway. LMAN2L has been associated with bipolar disorder.
Physical form
Solution in phosphate buffered saline, pH 7.4
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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Find documentation for the products that you have recently purchased in the Document Library.
Profile-based data base scanning for animal L-type lectins and characterization of VIPL, a novel VIP36-like endoplasmic reticulum protein.
Nufer O
The Journal of Biological Chemistry, 278(18), 15886-15896 (2003)
Homozygous missense mutation in the LMAN2L gene segregates with intellectual disability in a large consanguineous Pakistani family.
Rafiullah R
Journal of medical Genetics, 53(2), 138-144 (2016)
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