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SAB1403528

Monoclonal Anti-ADRA1A, (N-terminal) antibody produced in mouse

clone 5G8, purified immunoglobulin, buffered aqueous solution

Synonym(s):

ADRA1C, ADRA1L1, ALPHA1AAR

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203

Key Documents

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Product Name

Monoclonal Anti-ADRA1A, (N-terminal) antibody produced in mouse, clone 5G8, purified immunoglobulin, buffered aqueous solution

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

5G8, monoclonal

form

buffered aqueous solution

mol wt

antigen ~29.08 kDa

species reactivity

human

technique(s)

indirect ELISA: suitable
western blot: 1-5 μg/mL

isotype

IgG1κ

NCBI accession no.

NM_033303

UniProt accession no.

P35348

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... ADRA1A(148)

Physical form

Solution in phosphate buffered saline, pH 7.4

General description

Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. (provided by RefSeq)

Immunogen

ADRA1A (NP_150646, 1 a.a. ~ 27 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MVFLSGNASDSSNCTQPPAPVNISKAI

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
10239-5G8

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Daniel J García-Domínguez et al.
Molecular biology of the cell, 22(8), 1227-1239 (2011-02-25)
In the vertebrate neuroepithelium, the decision to differentiate is made by neural precursors soon after mitosis, when they are apically located. This process is controlled by lateral inhibitory signals triggered by the Delta/Notch pathway. During mitosis, the capacity of neural

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