SAB1305552
MONOCLONAL ANTI-LC3 (APG8) antibody produced in mouse
clone 166AT1234, IgG fraction of antiserum, buffered aqueous solution
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Synonym(s):
Autophagy-related protein LC3 A, Autophagy-related ubiquitin-like modifier LC3 A, MAP1 light chain 3-like protein 1, MAP1LC3A, Microtubule-associated proteins 1A/1B light chain 3A
UNSPSC Code:
12352203
NACRES:
NA.41
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biological source
mouse
Quality Level
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
166AT1234, monoclonal
form
buffered aqueous solution
mol wt
14272 Da
species reactivity
rat, mouse, human
technique(s)
immunofluorescence: 1:25
immunohistochemistry: 1:50-1:100
western blot: 1:1000
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... MAP1LC3A(84557)
Physical form
Supplied in PBS with 0.09% (W/V) sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Certificates of Analysis (COA)
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Xiaoming Shu et al.
Molecular medicine reports, 16(2), 1180-1188 (2017-06-07)
Peripheral blood T lymphocytopenia has previously been identified in polymyositis/dermatomyositis (PM/DM) patients. Therefore, the present study aimed to examine the potential role of autophagy in peripheral blood T cell survival in PM/DM patients. Transmission electron microscopy was used to detect
Matteo Bordoni et al.
Cells, 11(8) (2022-04-24)
Mitochondria alterations are present in tissues derived from patients and animal models, but no data are available for peripheral blood mononuclear cells (PBMCs) of ALS patients. This work aims to investigate mitophagy in PBMCs of sporadic (sALS) patients and how
Maomao Sun et al.
Frontiers in immunology, 12, 685523-685523 (2021-08-03)
Recent studies have shown that autophagy upregulation can attenuate sepsis-induced acute kidney injury (SAKI). The tumor suppressor p53 has emerged as an autophagy regulator in various forms of acute kidney injury (AKI). Our previous studies showed that p53 acetylation exacerbated
Rongrong Hua et al.
Journal of cellular biochemistry, 120(9), 15915-15923 (2019-05-14)
The sequential reactivation of mechanistic target of rapamycin (mTOR) inhibited autophagic flux in neurons exposed to oxygen-glucose deprivation/reperfusion (OGD/R), which was characterized by reduction of autophagosome formation and restriction of autolysosome degradation. However, its detailed molecular mechanism was still unknown.
Rongrong Hua et al.
International journal of molecular sciences, 19(5) (2018-05-08)
We have reported that conventional protein kinase Cγ (cPKCγ)-modulated neuron-specific autophagy improved the neurological outcome of mice following ischemic stroke through the Akt-mechanistic target of rapamycin (mTOR) pathway. However, its detailed molecular mechanism remains unclear. In this study, primary cortical
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