SAB1303130
ANTI-HSD17B2 (CENTER) antibody produced in rabbit
IgG fraction of antiserum, buffered aqueous solution
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Synonym(s):
17-beta-HSD 2, 17-beta-hydroxysteroid dehydrogenase type 2, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, E2DH, EDH17B2, Estradiol 17-beta-dehydrogenase 2, HSD17B2, Microsomal 17-beta-hydroxysteroid dehydrogenase, Testosterone 17-beta-dehydrogenase
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
42785 Da
species reactivity
human
technique(s)
flow cytometry: 1:10-1:50
immunohistochemistry: 1:10-1:50
western blot: 1:1000
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... HSD17B2(3294)
Related Categories
General description
HSD17B2 (Hydroxysteroid 17-β dehydrogenase 2) is a member of the short chain alcohol dehydrogenase superfamily expressed in non-steroidogenic human embryonic kidney cells.
Application
ANTI-HSD17B2 (CENTER) antibody produced in rabbit is suitable for flow cytometry (1:10-1:50), immunohistochemistry (1:50-1:100), and western blot: 1:250-1:500.
Biochem/physiol Actions
HSD17B2 (Hydroxysteroid 17-β dehydrogenase 2) is highly involved in the synthesis and metabolism of steroid hormones. It maintains the intracellular concentration of biologically active steroid hormones in a wide range of male and female human tissues. It catalyzes the interconversion of testosterone and androstenedione as well as estradiol and estrone through 17-β HSD activities. HSD17B2 also exhibits 20α-HSD activity toward 20α-dihydroprogesterone.
Physical form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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L Wu et al.
The Journal of biological chemistry, 268(17), 12964-12969 (1993-06-15)
17 beta-Hydroxysteroid dehydrogenase (17 beta-HSD) is an enzyme crucial to the regulation of intracellular levels of biologically active steroid hormones in a variety of tissues. Here, we report the isolation, structure, and characterization of a cDNA encoding the human 17
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