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Safety Information

SAB1105806

Sigma-Aldrich

Anti-ASB13 (215-225) antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-Ankyrin repeat and SOCS box-containing 13

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

200

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen predicted mol wt ~30 kDa

species reactivity

human

technique(s)

western blot: 1:500-1:2,000

UniProt accession no.

Q8WXK3

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ASB13(79754)

General description

Ankyrin repeat and SOCS box containing 13 (ASB13) is part of the ankyrin repeat and SOCS box (ASB) family and belongs to the suppressor of cytokine signaling (SOCS) box protein superfamily. It might interact with proteins like the RNA polymerase III subunit A and single-stranded DNA-binding protein. The gene encoding ASB13 is localized on human chromosome 10p15.1.

Immunogen

synthetic peptide corresponding to amino acids 215-225 of human ASB13

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

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WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes.
Kohroki J, et al.
FEBS Journal, 579(30), 6796-6802 (2005)
Genome-wide Cardiovascular Disease Risk of Sudden Deaths Between 5-40 Years in Turkish Population Investigation of Factors.
Cavlak G O C O, et al.
The Journal of Experimental Medicine, 6(12), 45-47 (2016)
Christina Aaen Andresen et al.
The Journal of biological chemistry, 289(4), 2043-2054 (2013-12-18)
The ankyrin and SOCS (suppressor of cytokine signaling) box (ASB) family of proteins function as the substrate recognition subunit in a subset of Elongin-Cullin-SOCS (ECS) E3 ubiquitin ligases. Despite counting 18 members in humans, the identity of the physiological targets

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