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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
3
biological source
rabbit
conjugate
unconjugated
antibody form
IgG fraction of antiserum
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~22 kDa
species reactivity
human
technique(s)
western blot: 1:500-1:2,000
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TM4SF19(116211)
General description
Transmembrane 4 L six family member 19 (TM4SF19) or osteoclast maturation-associated gene 4 protein (OCTM4) belongs to the transmembrane 4 L six superfamily. TM4SF19 gene is mapped to human chromosome 3q29.
Immunogen
synthetic peptide corresponding to amino acids 146-160 of human TM4SF19
Biochem/physiol Actions
Transmembrane 4 L six family member 19 (TM4SF19) expression is detected in the chronic heart disease samples especially in the cells, sera and tissues. It may contribute to atherosclerosis progression and may serve as a potential marker for screening atherosclerosis.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Adela Chirita Emandi et al.
Frontiers in pediatrics, 7, 270-270 (2019-07-25)
3q29 deletion syndrome is a rare disorder, causing a complex phenotype. Clinical features are variable and relatively non-specific. Our report aims to present an atypical, de novo deletion in chromosome band 3q29 in a preschool boy, first child of healthy
Yuji Kubota et al.
Nature communications, 13(1), 4063-4063 (2022-07-14)
Point-mutations of MEK1, a central component of ERK signaling, are present in cancer and RASopathies, but their precise biological effects remain obscure. Here, we report a mutant MEK1 structure that uncovers the mechanisms underlying abnormal activities of cancer- and RASopathy-associated
Li Ding et al.
Biochemical and biophysical research communications, 533(4), 1204-1211 (2020-10-17)
Atherosclerosis is a chronic vascular inflammatory disease that initially starts from an arterial intima lesion and endothelial barrier dysfunction. The purpose of this study was to investigate the role of TM4SF19, a recently identified member of the transmembrane 4L six
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