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Merck
CN

S9399

Staphylococcal enterotoxin A

from Staphylococcus aureus, lyophilized powder, enterotoxin

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About This Item

CAS Number:
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Quality level:
Technical Service
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Product Name

Staphylococcal enterotoxin A from Staphylococcus aureus,

Quality Level

contains

sodium phosphate buffer as balance

composition

Protein, ~10% Lowry

availability

not available in USA

impurities

Staphylococcal enterotoxin B (SEB), essentially free

solubility

H2O: complete 1 mg/ml, clear, colorless

storage temp.

2-8°C

General description

Staphylococcal enterotoxin A belongs to the family of staphylococcal exotoxins. It is secreted by Staphylococcus aureus, a Gram-positive bacteria.

Application

Staphylococcal enterotoxin A from Staphylococcus aureus has been used as an external standard in for the verification of TRANSIA assay kit, RIDASCREEN assay kit and Vidas Set 2 method. For in vitro toxin stimulation of mouse splenocytes.
Staphylococcal enterotoxin A from Staphylococcal aureus was injected peritoneally in mice to induce sepsis.10

Biochem/physiol Actions

Staphylococcal enterotoxin A from Staphylococcus aureus is leading agent that causes of food poisoning. A concentration of as little as 0.5 mg/ml is sufficient to result in nausea, vomiting, diarrhea and cramps.8 It stimulates the cell proliferation of peripheral lymphocytes, induces the production of interferons and is important for gut immunity against S. aureus infections.9 It acts as a super antigen for T-lymphocytes.

Packaging

Package size based on protein content


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

高风险级别生物产品--毒素类产品

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Marcin Kłak et al.
Scandinavian journal of infectious diseases, 42(5), 351-358 (2010-01-27)
Haemostatic balance shifts towards pro-coagulation during infection. Plasminogen, a key molecule of fibrinolysis, may play an important role in the pathogenesis of staphylococcal infections. In the present study, we assessed the impact of inhibition of plasminogen activation by tranexamic acid
Staphylococcal enterotoxin A (SEA).
L Spero et al.
Methods in enzymology, 78(Pt A), 331-336 (1981-01-01)
Determination of staphylococcal enterotoxins in cheese by immunoenzyme assays
<BIG>Jankovic V, et al.</BIG>
Archives of Biological Sciences, 64, 1449-1454 (2012)



Global Trade Item Number

SKUGTIN
S9399-.5MG04061832941462
S9399-.1MG04061832941455