S9071
Saikosaponin B2 from Bupleurum falcatnum
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About This Item
Empirical Formula (Hill Notation):
C24H68O13
Molecular Weight:
564.79
UNSPSC Code:
12352200
storage temp.
2-8°C
Application
Saikosaponins such as Saikosaponin B2 are used to help analyse and resolve the activities of herbal medicines such as Sho-saiko-to.
Biochem/physiol Actions
Saikosaponin B2 induces apoptosis in cultured melanoma cell lines through down regulation of PKC activity.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Sho-saiko-to: Japanese herbal medicine for protection against hepatic fibrosis and carcinoma.
Shimizu I.
Journal of Gastroenterology and Hepatology, 15, suppl D84-suppl D90 (2000)
I Sakaida et al.
Journal of hepatology, 28(2), 298-306 (1998-03-26)
A herbal medicine, Sho-saiko-to (TJ-9), has recently been orally administered to patients with chronic liver disease in Japan and has been reported to inhibit the development of hepatocellular carcinoma. The aim of this study was to investigate whether TJ-9 has
K Kayano et al.
Journal of hepatology, 29(4), 642-649 (1998-11-21)
It is of extreme importance to prevent liver fibrosis and subsequent progression to liver cirrhosis. The aim of our study was to elucidate in vitro whether Sho-saiko-to exerted inhibitory effects on hepatic stellate cells. Hepatic stellate cells were isolated from
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