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Safety Information

S9071

Sigma-Aldrich

Saikosaponin B2 from Bupleurum falcatnum

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About This Item

Empirical Formula (Hill Notation):
C24H68O13
Molecular Weight:
564.79
UNSPSC Code:
12352200

storage temp.

2-8°C

Application

Saikosaponins such as Saikosaponin B2 are used to help analyse and resolve the activities of herbal medicines such as Sho-saiko-to.

Biochem/physiol Actions

Saikosaponin B2 induces apoptosis in cultured melanoma cell lines through down regulation of PKC activity.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

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Sho-saiko-to: Japanese herbal medicine for protection against hepatic fibrosis and carcinoma.
Shimizu I.
Journal of Gastroenterology and Hepatology, 15, suppl D84-suppl D90 (2000)
I Sakaida et al.
Journal of hepatology, 28(2), 298-306 (1998-03-26)
A herbal medicine, Sho-saiko-to (TJ-9), has recently been orally administered to patients with chronic liver disease in Japan and has been reported to inhibit the development of hepatocellular carcinoma. The aim of this study was to investigate whether TJ-9 has
K Kayano et al.
Journal of hepatology, 29(4), 642-649 (1998-11-21)
It is of extreme importance to prevent liver fibrosis and subsequent progression to liver cirrhosis. The aim of our study was to elucidate in vitro whether Sho-saiko-to exerted inhibitory effects on hepatic stellate cells. Hepatic stellate cells were isolated from

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