All Photos(1)

Documents

S9009

Sar-Pro-Arg p-nitroanilide dihydrochloride

Name: Sar-Pro-Arg p-nitroanilide dihydrochloride
Brand: SIGMA

thrombin substrate, ≥97% (HPLC), powder

Sign Into View Organizational & Contract Pricing

All Photos(1)

About This Item

Empirical Formula (Hill Notation):

C₂₀H₃₀N₈O₅ · 2HCl

CAS Number:

75241-23-5

Molecular Weight:

535.42

MDL number:

MFCD00058168

UNSPSC Code:

12352204

PubChem Substance ID:

24899823

NACRES:

NA.32

product name

Sar-Pro-Arg p-nitroanilide dihydrochloride, thrombin substrate

Quality Level

300

Assay

≥97% (HPLC)

form

powder

solubility

water: 25 mg/mL, clear, colorless to light yellow

storage temp.

−20°C

SMILES string

Cl.CNCC(=O)N1CCCC1C(=O)NC(CCCNC(N)=N)C(=O)Nc2ccc(cc2)N(=O)=O

InChI

1S/C20H30N8O5.ClH/c1-23-12-17(29)27-11-3-5-16(27)19(31)26-15(4-2-10-24-20(21)22)18(30)25-13-6-8-14(9-7-13)28(32)33;/h6-9,15-16,23H,2-5,10-12H2,1H3,(H,25,30)(H,26,31)(H4,21,22,24);1H

InChI key

KMSNYOSWLIQVAN-UHFFFAOYSA-N

Substrates

Chromogenic substrate for thrombin.

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A clinical evaluation of automated chromogenic tests as substitutes for conventional prothrombin time and activated partial thromboplastin time tests.

A Duncan et al.

Clinical chemistry, 31(6), 853-855 (1985-06-01)

Automated procedures involving a chromogenic substrate sensitive to thrombin-sarcosine-Pro-Arg p-nitroanilide were compared with conventional tests for prothrombin times and activated partial thromboplastin times (APTT) and with specific assays for factors V, VII, VIII, IX, X, XI, and XII. The reproducibility

Development of broad-spectrum halomethyl ketone inhibitors against coronavirus main protease 3CL(pro).

Usman Bacha et al.

Chemical biology & drug design, 72(1), 34-49 (2008-07-10)

Coronaviruses comprise a large group of RNA viruses with diverse host specificity. The emergence of highly pathogenic strains like the SARS coronavirus (SARS-CoV), and the discovery of two new coronaviruses, NL-63 and HKU1, corroborates the high rate of mutation and

Protocols

Thrombin from Bovine Plasma

Thrombin is an endolytic serine protease that selectively cleaves the Arg–Gly bonds of fibrinogen to form fibrin and release fibrinopeptides A and B.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service