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Key Documents

Safety Information

S9008

Sigma-Aldrich

Anti-Staphylococcal Enterotoxin B antibody produced in rabbit

fractionated antiserum, lyophilized powder

Synonym(s):

Rabbit Anti-SEB

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25 G
CN¥603.89
100 G
CN¥1,514.28
500 G
CN¥5,897.74

CN¥603.89


Available to ship onApril 25, 2025Details


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25 G
CN¥603.89
100 G
CN¥1,514.28
500 G
CN¥5,897.74

About This Item

MDL number:
UNSPSC Code:
12352203
NACRES:
NA.46

CN¥603.89


Available to ship onApril 25, 2025Details


Request a Bulk Order

biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

fractionated antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

Staphylococcus aureus

packaging

vial of 2 mL lyophilized antiserum

technique(s)

indirect ELISA: 1:150,000-1:250,000

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This Item
P3768H7006P6757
assay

≥99% (titration)

assay

≥99% (titration)

assay

≥99.0% (titration)

assay

≥99% (titration)

Quality Level

200

Quality Level

200

Quality Level

400

Quality Level

400

form

crystalline powder

form

crystalline powder

form

powder

form

crystalline powder

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing

application(s)

diagnostic assay manufacturing
general analytical (
)
life science and biopharma
metabolomics

application(s)

diagnostic assay manufacturing

solubility

0.1 M NaOH: 250 mg/mL, clear, colorless

solubility

water: 0.5 g/mL, clear, colorless

solubility

water: 0.1 M, clear, colorless

solubility

1 M NaOH: 20 + 80 mL g, clear, colorless

pH

4.5-4.7

pH

-

pH

10-12 (1 M in water)

pH

-

General description

Staphylococcal enterotoxin B is a toxic bacterial superantigen. The staphylococcal enterotoxins family have high sequence similarity.

Immunogen

Staphylococcal enterotoxin B from Staphylococcus aureus.

Application

Anti-Staphylococcal Enterotoxin B antibody produced in rabbit has been used:
  • to conjugate with hollow gold nanosphere and as a component of lateral flow immunoassay strip
  • in antibody sandwich immunoassay
  • for coupling with magnetic beads for detection assay

Biochem/physiol Actions

Staphylococcal enterotoxin B (SEB) is a superantigen that binds to class II MHC molecules on antigen presenting cells. It stimulates large populations of T cells resulting in acute toxic shock syndrome. It is resistant to denaturation and causes outbreaks of food poisoning that includes emetic responses, diarrhea and GI inflammation.
Staphylococcal enterotoxin B compromises the immune system by triggering inflammation and cytokine release.

Physical form

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2.

Reconstitution

Reconstitute with 2 ml deionized water.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

常规特殊物品

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Certificates of Analysis (COA)

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Lily Zhang et al.
Toxins, 5(10), 1859-1871 (2013-10-25)
The functional activity of superantigens is based on capacity of these microbial proteins to bind to both the β-chain of the T cell receptor (TcR) and the major histocompatibility complex (MHC) class II dimer. We have previously shown that a
A rapid and sensitive magnetic bead-based immunoassay for the detection of staphylococcal enterotoxin B for high-through put screening
Alefantis T, et al.
Molecular and Cellular Probes, 18(6), 379-382 (2004)
Electrogenerated indium tin oxide-coated glass surface with photosensitive interfaces: Surface analysis
Konry T, et al.
Biosensors And Bioelectronics, 22(9-10), 2230-2236 (2007)
Staphylococcal enterotoxins
Balaban N and Rasooly A
International Journal of Food Microbiology, 61(1), 1-10 (2000)
Application of a SERS-based lateral flow immunoassay strip for the rapid and sensitive detection of staphylococcal enterotoxin B
Hwang J, et al.
Nanoscale, 8(22), 11418-11425 (2016)

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