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Merck
CN

S7626

Succinic anhydride

Synonym(s):

Dihydro-2,5-furandione

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About This Item

Empirical Formula (Hill Notation):
C4H4O3
CAS Number:
Molecular Weight:
100.07
EC Number:
203-570-0
UNSPSC Code:
12352103
MDL number:
Beilstein/REAXYS Number:
108441
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InChI

1S/C4H4O3/c5-3-1-2-4(6)7-3/h1-2H2

InChI key

RINCXYDBBGOEEQ-UHFFFAOYSA-N

SMILES string

O=C1CCC(=O)O1

vapor density

3.5 (vs air)

vapor pressure

1 mmHg ( 92 °C)

bp

261 °C (lit.)

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Application

Reagent for the succinylation of lysine in proteins.

Regulatory Information

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Wenlian Zhu et al.
Magnetic resonance in medicine, 59(4), 679-685 (2008-02-28)
Pretargeting of receptors is a useful approach in molecular imaging and therapy to reduce background noise or toxicity and enhance selectivity. In this study a three-step pretargeting approach that includes a biotinylated antibody, avidin/streptavidin, and a biotinylated imaging agent is
Peisheng Xu et al.
Biomacromolecules, 11(9), 2352-2358 (2010-08-11)
Zwitterionic chitosan, a chitosan derivative with a unique pH-dependent charge profile, was employed to create a stealth coating on the cationic surface of drug carriers. Zwitterionic chitosans were synthesized by amidation of chitosan with succinic anhydride. The succinic anhydride-conjugated chitosan
Jean-François Poulin et al.
International journal of pharmaceutics, 405(1-2), 47-54 (2010-12-07)
The use of succinylated β-lactoglobulin as a novel functional tablet excipient for the protection of probiotic bacteria against the adverse gastric conditions and their delivery in the intestine was studied. Tablets were produced by direct compression of a dry mixture
Christian J Koehler et al.
Analytical chemistry, 83(12), 4775-4781 (2011-05-03)
Recently, we introduced a novel approach for protein quantification based on isobaric peptide termini labeling (IPTL). In IPTL, both peptide termini are dervatized in two separate chemical reactions with complementary isotopically labeled reagents to generate isobaric peptide pairs. Here, we
Yu-Li Lin et al.
PLoS genetics, 5(10), e1000680-e1000680 (2009-10-10)
The p53 family activates many of the same genes in response to DNA damage. Because p63 and p73 have structural differences from p53 and play distinct biological functions in development and metastasis, it is likely that they activate a unique

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