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S5519

Sigma-Aldrich

Lipoprotein Deficient Serum from human plasma

sterile-filtered, frozen liquid

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UNSPSC Code:
12352202
NACRES:
NA.26

biological source

human

Quality Level

200

sterility

sterile-filtered

form

frozen liquid

quality

No banding correlating to lipoprotein observed by Agarose Electrophoresis

composition

protein, ≥50 mg/mL biuret

origin

USA origin

concentration

≥50 mg protein/mL Biuret

technique(s)

cell culture | mammalian: suitable

UniProt accession no.

P02647
P02649
P02654
P02656
P04114
P06727
Q6Q788

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... APOA1(335) , APOA4(337) , APOA5(116519) , APOB(338) , APOC1(341) , APOC3(345) , APOE(348)

Related Categories

Biochem/physiol Actions

Lipoprotein deficient serum was shown to inhibit the transfer of unesterified cholesterol from LDL to HDL.

Preparation Note

Dialyzed against Dulbecco′s phosphate buffered saline, pH 7.2-7.3

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

高风险级别生物产品--人源产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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E Velazquez et al.
Biomedica biochimica acta, 50(9), 1109-1114 (1991-01-01)
The in vitro transfer of radiolabelled unesterified cholesterol from human low- and very low- to high-density lipoproteins in the presence of either lipoprotein deficient serum or bovine serum albumin has been studied. The rate of transfer was faster from LDL
Inés Pineda Torra et al.
Molecular and cellular biology, 28(8), 2626-2636 (2008-02-06)
Dysregulation of liver X receptor alpha (LXRalpha) activity has been linked to cardiovascular and metabolic diseases. Here, we show that LXRalpha target gene selectivity is achieved by modulation of LXRalpha phosphorylation. Under basal conditions, LXRalpha is phosphorylated at S198; phosphorylation
Zehra Yildirim et al.
EMBO molecular medicine, 14(4), e15344-e15344 (2022-02-23)
Fragile X Mental Retardation protein (FMRP), widely known for its role in hereditary intellectual disability, is an RNA-binding protein (RBP) that controls translation of select mRNAs. We discovered that endoplasmic reticulum (ER) stress induces phosphorylation of FMRP on a site
Shaoqin Zheng et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 9(28), e2200750-e2200750 (2022-08-18)
Frizzled (Fzd) proteins are Wnt receptors and play essential roles in development, homeostasis, and oncogenesis. How Wnt/Fzd signaling is coupled to physiological regulation remains unknown. Cholesterol is reported as a signaling molecule regulating morphogen such as Hedgehog signaling. Despite the

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