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S5187

Sigma-Aldrich

Monoclonal Anti-SNAP-25 antibody produced in mouse

clone SP12, purified immunoglobulin, buffered aqueous solution

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MDL number:
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

SP12, monoclonal

form

buffered aqueous solution

species reactivity

pig, hamster, rat, human

technique(s)

immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable

isotype

IgG1

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SNAP25(6616)
rat ... Snap25(25012)

Immunogen

crude human synaptic precipitate.

Physical form

Solution in phosphate buffered saline containing 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Regulatory Information

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Rosane Aparecida Ribeiro et al.
Experimental physiology, 97(9), 1065-1073 (2012-05-01)
Ageing is associated with an increased impairment in glucose homeostasis and an increased incidence of type 2 diabetes. In this study, we evaluated β-cell function and its implications for glucose homeostasis in 24-month-old female Wistar rats. Aged rats showed lower plasma
Katsusuke Hata et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 27(52), 14481-14493 (2007-12-28)
Characterization of neuromuscular junction formation and function in mice lacking all neural cell adhesion molecule (NCAM) isoforms or only the 180 isoform demonstrated that the 180 isoform was required at adult synapses to maintain effective transmission with repetitive stimulation whereas
Shiho Honma et al.
Anatomical record (Hoboken, N.J. : 2007), 293(6), 1070-1080 (2010-02-27)
Distribution of three soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptor (SNARE) proteins, syntaxin-1, synaptosomal-associated protein of 25 kDa (SNAP-25), and vesicle-associated membrane protein-2 (VAMP-2), was examined in dental pulp and periodontal ligament of the rat incisor. In the trigeminal ganglion
Yoshitaka Ohtubo et al.
The European journal of neuroscience, 35(11), 1661-1671 (2012-04-03)
Taste buds contain two types of taste receptor cells, inositol 1,4,5-triphosphate receptor type 3-immunoreactive cells (type II cells) and synaptosomal-associating protein-25-immunoreactive cells (type III cells). We investigated their postnatal development in mouse fungiform taste buds immunohistochemically and electrophysiologically. The cell
Satoshi Asano et al.
Biology open, 3(6), 463-474 (2014-05-09)
We previously reported that phospholipase C-related catalytically inactive protein (PRIP)-knockout mice exhibited hyperinsulinemia. Here, we investigated the role of PRIP in insulin granule exocytosis using Prip-knockdown mouse insulinoma (MIN6) cells. Insulin release from Prip-knockdown MIN6 cells was higher than that

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