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S4506

Sigma-Aldrich

Sodium diatrizoate hydrate

≥98.0% purity, powder

Synonym(s):

3,5-Bis(acetylamino)-2,4,6-triiodobenzoic acid, sodium salt, 3,5-Diacetamido-2,4,6-triiodobenzoic acid sodium salt, Diatrizoic acid sodium salt hydrate

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About This Item

Empirical Formula (Hill Notation):
C11H8I3N2NaO4 · xH2O
CAS Number:
Molecular Weight:
635.90 (anhydrous basis)
Beilstein:
4082984
UNSPSC Code:
12352207
PubChem Substance ID:
NACRES:
NA.75

product name

Sodium diatrizoate hydrate, ≥98.0%

Quality Level

Assay

≥98.0%

form

powder

composition

Water (by Karl Fischer): ≤ 11.0%

color

white to off-white

mp

261 °C

solubility

H2O: 350 mg/mL, clear to slightly hazy

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

O.[Na+].CC(=O)Nc1c(I)c(NC(C)=O)c(I)c(C([O-])=O)c1I

InChI

1S/C11H9I3N2O4.Na.H2O/c1-3(17)15-9-6(12)5(11(19)20)7(13)10(8(9)14)16-4(2)18;;/h1-2H3,(H,15,17)(H,16,18)(H,19,20);;1H2/q;+1;/p-1

InChI key

ZZBYVHJZBJEHFI-UHFFFAOYSA-M

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Application

Sodium diatrizoate hydrate has been used in spore purification. It has also been used in the isolation of plasma lymphocytes, monocytes, and dendritic cells.Sodium diatrizoate is also suitable as a density gradient reagent in blood cell separation. It has also been utilized as a radiological contrast agent.

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Diffusion of MRI and CT contrast agents in articular cartilage under static compression.
Shafieyan Y, et al.
Biophysical Journal, 107(2), 485-492 (2014)
Sandra Eickhoff et al.
Veterinary immunology and immunopathology, 101(1-2), 109-121 (2004-07-21)
Quantitative analysis of phagocytosis and oxidative burst in canine polymorphonuclear (PMN) cells was performed by flow cytometry techniques. Different concentrations of phorbol myristate acetate (PMA) were used to modulate PMN phagocytosis. A low concentration of PMA (3 nmol) resulted in
Xi Lin et al.
Vaccine, 26(52), 6814-6817 (2008-10-28)
Density gradient centrifugation was used for identification of particulates in vaccines formulated with aluminum phosphate (AlPO(4)) adjuvant. Protein-derived particulates are sporadically seen in protein pre-filled formulations where siliconized syringes are employed. These particulates are difficult to distinguish from the AlPO(4)
H T Chern et al.
Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 17(4), 143-151 (1993-10-01)
Eighteen pancreata from adult mongrel dogs were used for the study of islet isolation. The pancreas was distended with collagenase in Hanks' solution. The automated screen method and Histopaque Ficoll gradients were used to isolate and purify the canine islets.
Jong-Hwa Park et al.
Journal of microbiology and biotechnology, 29(9), 1383-1390 (2019-08-23)
In this study, we expressed cotA laccase from Bacillus subtilis on the surface of B. subtilis spores for efficient decolorization of synthetic dyes. The cotE, cotG, and cotY genes were used as anchoring motifs for efficient spore surface display of

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