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S4500

Sigma-Aldrich

L-Serine

≥99% (HPLC), ReagentPlus®

Synonym(s):

(S)-2-Amino-3-hydroxypropionic acid

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About This Item

Linear Formula:
HOCH2CH(NH2)CO2H
CAS Number:
56-45-1
Molecular Weight:
105.09
Beilstein:
1721404
EC Number:
200-274-3
MDL number:
MFCD00064224
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24899605
NACRES:
NA.26

product name

L-Serine, ReagentPlus®, ≥99% (HPLC)

Quality Level

200

product line

ReagentPlus®

Assay

≥99% (HPLC)

form

powder

color

white to off-white

mp

222 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless

application(s)

detection

storage temp.

room temp

SMILES string

N[C@@H](CO)C(O)=O

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

InChI key

MTCFGRXMJLQNBG-REOHCLBHSA-N

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Application

L-Serine has been used in the preparation of Tris-BSAN buffer for homogenization. It has also been used for quantitative analysis of excretion of polypeptides in normal urine.

Biochem/physiol Actions

L-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system. L-Serine also has a role in cellular proliferation.
Precursor of glycine by serine hydroxymethyltransferase.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Taiga Okumura et al.
Scientific reports, 9(1), 3520-3520 (2019-03-07)
Radiocaesium-bearing microparticles (CsMPs) composed of silicate glass were released by the Fukushima Daiichi Nuclear Power Plant accident in March 2011. Since CsMPs contain a high concentration of radiocaesium, their dynamics and fate in the environment are urgent issues to be
Analysis of GSH and GSSG after derivatization with N-ethylmaleimide
Nature Protocols, 8(9) (2003)
Quantitative amino acid and proteomic analysis: Very low excretion of polypeptides >750 Da in normal urine
Anthony G.W.Norden
Kidney International, 66(5) (2004)
Abel Lajtha, Simo S. Oja, Pirjo Saransaari, Arne Schousboe
Handbook of Neurochemistry and Molecular Neurobiology: Amino Acids and Peptides in the Nervous System , 4 (2007)
Taiga Okumura et al.
Scientific reports, 8(1), 9707-9707 (2018-06-28)
Radiocesium-bearing microparticles (CsPs) substantially made of silicate glass are a novel form of radiocesium emitted from the broken containment vessel of Fukushima Dai-ichi nuclear power plant. CsPs have a potential risk of internal radiation exposure caused by inhalation. Radiation-contaminated waste
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