Skip to Content
Merck
CN

S3388

Sulforhodamine 101 acid chloride

Technical grade

Synonym(s):

Sulforhodamine 101 sulfonyl chloride

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C31H29ClN2O6S2
CAS Number:
82354-19-6
Molecular Weight:
625.15
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
24899558
MDL number:
MFCD00012406
Beilstein/REAXYS Number:
8667894

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C31H29ClN2O6S2/c32-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-33-13-3-7-22(28(18)33)30(24)40-31-23-8-4-14-34-12-2-6-19(29(23)34)16-25(27)31/h9-10,15-17H,1-8,11-14H2

SMILES string

[O-]S(=O)(=O)c1cc(ccc1C2=C3C=C4CCC[N+]5=C4C(CCC5)=C3Oc6c7CCCN8CCCc(cc26)c78)S(Cl)(=O)=O

InChI key

MPLHNVLQVRSVEE-UHFFFAOYSA-N

form

powder

composition

Dye content, ~75%

impurities

~1 mol/mol chloroform as solvent of crystallization

solubility

methanol: 10 mg/mL

fluorescence

λex 586 nm; λem 605 nm in H2O

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

−20°C

General description

Sulforhodamine 101 is a red fluorescent dye. It is water-soluble, amphoteric rhodamine. The dye can be specifically used as a marker of astroglia in the neocortex. It is commonly used for brain imaging. Studies suggest that sulforhodamine 101 may be used as an epileptogenic agent.

Application

Sulforhodamine 101 acid chloride has been used in an encapsulated fluorescent probe as a model drug to study drug-delivery properties of rhamnogalacturonan-I based microcapsules. It has also been used in confocal imaging as an astrocyte specific dye.

Other Notes

Mixture of the two monosulfonyl chloride derivatives of sulforhodamine 101.

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

易制毒化学品（2类）
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
068K3799
058K3784
038K3776
028K1387
117K3780

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jorge O Escobedo et al.
Natural product communications, 7(3), 317-320 (2012-05-02)
Understanding cellular mechanisms of ototoxic and nephrotoxic drug uptake, intracellular distribution, and molecular trafficking across cellular barrier systems aids the study of potential uptake blockers that preserve sensory and renal function during critical life-saving therapy. Herein we report the design
Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo.
Nimmerjahn A
Nature Materials, 1(1), 31-37 (2004)
Keiji Numata et al.
Biomacromolecules, 13(5), 1383-1389 (2012-04-05)
We developed a facile and quick ethanol-based method for preparing silk nanoparticles and then fabricated a biodegradable and biocompatible dual-drug release system based on silk nanoparticles and the molecular networks of silk hydrogels. Model drugs incorporated in the silk nanoparticles
Sara Seabrooke et al.
The Journal of experimental biology, 215(Pt 17), 2945-2949 (2012-08-10)
We describe a method for calculating rates of fluorochrome transport from unstirred layer (USL) concentration gradients measured using confocal microscopy. Isolated Malpighian tubules or guts of Drosophila melanogaster were secured to depression slides and bathed in saline containing a fluorescent
Yang Liu et al.
Pharmaceutical research, 29(12), 3273-3277 (2012-07-19)
The biodistribution of Lipid/Calcium/Phosphate (LCP) nanoparticles (NPs) in tumor-bearing mice was investigated using fluorescence imaging. A quantitative validation of this method was done by (3)H and (111)In labeling of the nanoparticles. The biodistribution of LCP NPs containing oligonucleotides was investigated
View All Related Papers

Related Content

Product Information Sheet - S3388

Product Information Sheet

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service