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Merck
CN

S2770

Sodium hydroxide solution

1.0 N, BioReagent, suitable for cell culture

Synonym(s):

Caustic Soda, Lye, NaOH, Soda

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About This Item

Linear Formula:
NaOH
CAS Number:
1310-73-2
Molecular Weight:
40.00
MDL number:
MFCD00003548
UNSPSC Code:
12352316
PubChem Substance ID:
24899535
NACRES:
NA.71

Key Documents

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vapor pressure

3 mmHg ( 37 °C)

Quality Level

200

sterility

sterile-filtered

product line

BioReagent

form

solution

concentration

1.0 N

technique(s)

cell culture | mammalian: suitable

SMILES string

[OH-].[Na+]

InChI

1S/Na.H2O/h;1H2/q+1;/p-1

InChI key

HEMHJVSKTPXQMS-UHFFFAOYSA-M

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General description

Sodium hydroxide is a strong alkali. Its reaction with acid yields salt and water. Sodium hydroxide solution has many industrial applications including dyes and drugs. It has the ability to disintegrate lignin and hence is used in paper manufacturing. Sodium hydroxide has high melting of about 318°C.

Application

Sodium hydroxide solution has been used:
  • to neutralize collagen type I solution phosphate-buffered saline for its use in 3D cell culture technique
  • to dissolve phosphate chains in phosphate glass for optical characterisation
  • as a component of transfer medium used for cell culture
  • as a general titration base for cell culture applications.

Pictograms

Corrosion
GHS05

Signal Word

Danger

Hazard Statements

H290,H314

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

Storage Class Code

8B - Non-combustible corrosive hazardous materials

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
RNBL6715
RNBL4710
RNBL4177
RNBL3666
RNBL2228

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Isolation and culture of human endometrial epithelial cells and stromal fibroblasts
Chen JC and Roan NR
Bio-protocol, 5(20) (2015)
Sodium, 21-21 (2002)
Matrix dimensions, stiffness, and structural properties modulate spontaneous chondrogenic commitment of mouse embryonic fibroblasts
Fernandez MT
Tissue Engineering: Part A, 20(7-8), 1145-1155 (2013)
Optical characterisation of hydroxide catalysed bonds applied to phosphate glass
Optifab, 10448, 1044825-1044825 (2017)
Konstantinos A Polyzos et al.
Cardiovascular research, 106(2), 295-302 (2015-03-10)
Atherosclerosis is a chronic inflammatory disease that is initiated by the retention and accumulation of low-density lipoprotein in the artery, leading to maladaptive response of cells from the immune system and vessel wall. Strong evidence implicates indoleamine 2,3-dioxygenase (IDO), the
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Product Information Sheet - S2770

Product Information Sheet

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