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S2501

Sigma-Aldrich

Spermidine trihydrochloride

≥98% (TLC)

Synonym(s):

N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride

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About This Item

Linear Formula:
NH2(CH2)3NH(CH2)4NH2 · 3HCl
CAS Number:
334-50-9
Molecular Weight:
254.63
Beilstein:
3552356
EC Number:
206-379-0
MDL number:
MFCD00012918
UNSPSC Code:
12352204
PubChem Substance ID:
24277993
NACRES:
NA.32

biological source

microbial
synthetic

Quality Level

200

Assay

≥98% (TLC)

form

powder

mp

257-259 °C (lit.)

solubility

water: 100 mg/mL, clear, colorless

storage temp.

room temp

SMILES string

Cl[H].Cl[H].Cl[H].NCCCCNCCCN

InChI

1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H

InChI key

LCNBIHVSOPXFMR-UHFFFAOYSA-N

Gene Information

human ... NOS1(4842)

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General description

The nitric oxide synthase (nNOS) gene is localized on human chromosome 12q24.22. The enzyme is involved in the production of nitric oxide.

Application

Spermidine trihydrochloride has been used in fourier transform infrared spectroscopy (FTIR)characterization and in zeta-potential measurements.

Biochem/physiol Actions

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity.

Caution

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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