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Merck
CN

S2192

S9 from Liver, Pooled

from mouse(CD-1), male, 20 mg/mL protein basis, vial of 1.0 mL

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About This Item

NACRES:
NA.47
UNSPSC Code:
12161501
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Product Name

S9 from Liver, Pooled, from mouse(CD-1), male, 20 mg/mL protein basis, vial of 1.0 mL

biological source

mouse (CD-1)

packaging

vial of 1.0 mL

concentration

20 mg/mL protein

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Quality Level

Gene Information

mouse ... Rps9(76846)

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Biochem/physiol Actions

Post-mitochondrial supernatant fraction from homogenized liver. Source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.
The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. Known to be a rich source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.
The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. They are known to be a rich source of drug metabolizing enzymes including P-450. S9 pools are useful in the study of xenobiotic metabolism and drug interactions. They are used in the Ames test, which is a method that uses bacteria to test if a given chemical causes mutations in the genetic material of a given test organism.

Physical form

Supplied as a solution in 150 mM KCl, 50 mM Tris buffer, pH 7.2 and 2 mM EDTA.

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

低风险生物材料
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The Ames Salmonella/microsome mutagenicity assay.
Mortelman K and Zeiger E
Mutation Research, 455(1-2), 29-60 (2000)
An improvement of the Ames test using a modified human liver S9 preparation.
Hakura A
Journal of Pharmacological and Toxicological Methods, 46(3), 169-172 (2001)

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