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S1402

Sulforhodamine B sodium salt

Name: Sulforhodamine B sodium salt
Brand: SIGMA

powder, BioReagent, suitable for cell culture

Synonym(s):

Kiton Red 620

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About This Item

Empirical Formula (Hill Notation):

C₂₇H₂₉N₂NaO₇S₂

CAS Number:

3520-42-1

Molecular Weight:

580.65

EC Number:

222-529-8

UNSPSC Code:

12352207

NACRES:

NA.75

PubChem Substance ID:

24899477

MDL number:

MFCD00010180

Colour Index Number:

45100

Beilstein/REAXYS Number:

3886008

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Properties

biological source

synthetic (organic)

Quality Level

100

product line

BioReagent

form

powder

composition

Dye content, ~75%

technique(s)

cell culture | mammalian: suitable

solubility

methanol: 1 mg/mL

fluorescence

λ_ex 565 nm; λ_em 586 nm in H₂O

SMILES string

[Na+].CCN(CC)c1ccc2c(OC3=CC(\C=CC3=C2c4ccc(cc4S([O-])(=O)=O)S([O-])(=O)=O)=[N+](\CC)CC)c1

InChI

1S/C27H30N2O7S2.Na/c1-5-28(6-2)18-9-12-21-24(15-18)36-25-16-19(29(7-3)8-4)10-13-22(25)27(21)23-14-11-20(37(30,31)32)17-26(23)38(33,34)35;/h9-17H,5-8H2,1-4H3,(H-,30,31,32,33,34,35);/q;+1/p-1

InChI key

SXQCTESRRZBPHJ-UHFFFAOYSA-M

Description

General description

Sulforhodamine B is a rhodamine derived aminoxanthene dye. It contains two sulfonic acids groups which separate in alkaline condition.

Application

Sulforhodamine B sodium salt has been used:

for relative total cell mass quantification
to investigate the viscosity of coacervates
as a molecular rotor for microviscosity determination in aerosol droplets

Biochem/physiol Actions

Sulforhodamine B sodium salt is useful to measure cell biomass and also for cytotoxicity screening.

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Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation (2012)

Bioconjugate Techniques, 317-317 (1996)

Alternative Oxidase Attenuates Cigarette Smoke-induced Lung Dysfunction and Tissue Damage.

Luca Giordano et al.

American journal of respiratory cell and molecular biology, 60(5), 515-522 (2018-10-20)

Cigarette smoke (CS) exposure is the predominant risk factor for the development of chronic obstructive pulmonary disease (COPD) and the third leading cause of death worldwide. We aimed to elucidate whether mitochondrial respiratory inhibition and oxidative stress are triggers in

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Global Trade Item Number

SKU	GTIN
S1402-1G	04061836910730
S1402-5G	04061836910792
S1402-25G	04061836910754