S1314
Monoclonal Anti-SERCa2 ATPase antibody produced in mouse
clone 2A7-A1, ascites fluid
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About This Item
Conjugate:
unconjugated
Clone:
2A7-A1, monoclonal
Application:
IP, WB
Citations:
17
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
2A7-A1, monoclonal
mol wt
antigen 110 kDa
contains
0.05% sodium azide
species reactivity
guinea pig, human, canine, mouse, rat, rabbit
technique(s)
immunoprecipitation (IP): suitable, western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... ATP2A2(488)
mouse ... Atp2a2(11938)
rat ... Atp2a2(29693)
General description
SERCa2 ATPase (sarco/endoplasmic reticulum calcium-ATPase 2) is also known as ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2). It codes for SERCA2a and SERCA2b, that are expressed in all tissues. SERCA2a is highly expressed in heart. SERCa2 is located on human chromosome 12q24.1.
Immunogen
canine cardiac sarcoplasmic reticulum vesicles
Application
Anti-SERCa2 ATPase antibody has been used in western blotting and immunocytochemistry.
Biochem/physiol Actions
Mutation of SERCa2 ATPase (sarco/endoplasmic reticulum calcium-ATPase 2) or ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2) causes Dyskeratosis follicularis. SERCA2a plays a major role in controlling cardiomyocyte Ca2+. ATP2A2 mutation may cause Darier disease (DD).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
动物来源生物产品
常规特殊物品
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Related Content
Datasheet
Modulation of sarcoplasmic reticulum Ca(2+)-ATPase by chronic and acute exposure to peroxynitrite
Gutierrez-Martin Y, et al.
European Journal of Biochemistry, 271(13), 2647-2657 (2004)
[Analysis of ATP2A2 gene mutations in a pedigree and a sporadic case with Darier disease]
Zhao X, et al.
Zhonghua yi xue yi chuan xue za zhi (Chinese Journal of Medical Genetics), 33(5), 641-644 (2016)
Clinical case of acral hemorrhagic Darier's disease is not caused by mutations in exon 15 of the ATP2A2 gene
Pecina-Slaus N, et al.
Collegium Antropologicum, 27(1), 125-133 (2003)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| S1314-100UL | 04061836910655 |