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Merck
CN

S1002

Saccharin sodium salt hydrate

≥98.0% (titration)

Synonym(s):

2,3-Dihydro-3-oxobenzisosulfonazole sodium salt, 2-Sulfobenzoic acid imide sodium salt, o-Sulfobenzimide sodium salt, Saccharin soluble

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About This Item

Empirical Formula (Hill Notation):
C7H4NNaO3S · xH2O
CAS Number:
82385-42-0
Molecular Weight:
205.17 (anhydrous basis)
UNSPSC Code:
12164504
NACRES:
NA.25
PubChem Substance ID:
24899456
EC Number:
204-886-1
Beilstein/REAXYS Number:
3599229
MDL number:
MFCD00149605
Assay:
≥98.0% (titration)

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Product Name

Saccharin sodium salt hydrate, ≥98.0% (titration)

InChI

1S/C7H5NO3S.Na.H2O/c9-7-5-3-1-2-4-6(5)12(10,11)8-7;;/h1-4H,(H,8,9);;1H2/q;+1;/p-1

InChI key

ILJOYZVVZZFIKA-UHFFFAOYSA-M

SMILES string

[Na+].[H]O[H].[O-]C1=NS(=O)(=O)c2ccccc12

assay

≥98.0% (titration)

sweetness

300 × sucrose

Quality Level

200

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Application


  • Application of a colorimetric technique in quality control for printed pediatric orodispersible drug delivery systems containing propranolol hydrochloride.: This article discusses the use of a colorimetric method to ensure quality control in 3D printed pediatric drug delivery systems, incorporating saccharin sodium salt hydrate as a sweetener, emphasizing its role in improving the taste and compliance of pediatric medications (Vakili et al., 2016).

Biochem/physiol Actions

′First generation′ synthetic sugar alternative that has been studied for its carcinogenic potential.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM7515
BCCH3969
BCCD3294
BCCB4001
BCBZ8610

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Seth R Batten et al.
Physiology & behavior, 213, 112729-112729 (2019-11-05)
Although hormonal and metabolic factors are well known to influence obesity, recent evidence suggests that obesity may be influenced also by changes in reward sensitivity akin to that seen in other 'reward pathologies', like substance use disorders. The current study
Robert A Boakes et al.
Physiology & behavior, 218, 112822-112822 (2020-02-01)
Rats first given 24-h access to 10% sucrose for 4 or 12 days (Stage 1) were then switched to a saccharin solution for a 12-day Stage 2. The initial result of this switch was that these Sucrose groups drank less
Valentina Sabino et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 34(6), 1482-1493 (2008-10-24)
Sigma-Receptors (SigRs) have been implicated in behavioral and appetitive effects of psychostimulants and may also modulate the motivating properties of ethanol. This study tested the hypothesis that SigRs modulate ethanol reinforcement and contribute to excessive ethanol intake. The effects of
Simone Rehn et al.
Physiology & behavior, 207, 15-27 (2019-05-06)
When animals are given access to a palatable food or drink on some days but not on others, the amount they consume can far exceed the daily amounts consumed by controls given daily access. A previous study demonstrated such bingeing
Rhian Alice Ceredig et al.
Frontiers in molecular neuroscience, 12, 324-324 (2020-03-03)
Neuropathic pain is a challenging condition for which current therapies often remain unsatisfactory. Chronic administration of β2 adrenergic agonists, including formoterol currently used to treat asthma and chronic obstructive pulmonary disease, alleviates mechanical allodynia in the sciatic nerve cuff model
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