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Merck
CN

S0652

Sucrose octasulfate–aluminum complex

Synonym(s):

Sucralfate

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About This Item

CAS Number:
54182-58-0
PubChem Substance ID:
329824435
UNSPSC Code:
12352201
NACRES:
NA.25
EC Number:
259-018-4

Key Documents

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InChI key

JTZPPHUZZDKEOC-RBQAPOGLSA-A

InChI

1S/C11H20O35S8.16Al.40H2O/c12-47(13,14)36-1-3-4(41-49(18,19)20)5(42-50(21,22)23)6(43-51(24,25)26)9(38-3)39-11(2-37-48(15,16)17)8(45-53(30,31)32)7(44-52(27,28)29)10(40-11)46-54(33,34)35;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/h3-10H,1-2H2,(H,12,13,14)(H,15,16,17)(H,18,19,20)(H,21,22,23)(H,24,25,26)(H,27,28,29)(H,30,31,32)(H,33,34,35);;;;;;;;;;;;;;;;;40*1H2/q;16*+3;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/p-48/t3-,4-,5+,6-,7+,8+,9+,10-,11-;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/m1......................................................../s1

SMILES string

O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al+]O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.O[Al](O)O.[O-]S(=O)(=O)OC[C@H]1O[C@@H](O[C@]2(COS([O-])(=O)=O)O[C@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O

form

powder

impurities

<0.5% chloride content

color

white to almost white

storage temp.

2-8°C

Quality Level

200

Gene Information

human ... PGA5(5222)

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Analysis Note

Minimum 30% sucrose octasulfate (HPLC)

Biochem/physiol Actions

An alkaline aluminum−sucrose complex which inhibits peptic hydrolysis and raises gastric pH.

Other Notes

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000447216
0000447216
0000386319
0000381904
0000381904

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Jan Calissendorff et al.
Endocrine research, 37(3), 154-162 (2012-05-25)
Alcohol stimulates appetite. Ghrelin, obestatin, glucagon-like peptide 1 and leptin are putative mediators. We studied whether alcohol ingestion affects serum levels of these peripheral hormones, and if gastroprotective sucralfate prevents such an effect. Ten participants were investigated on four occasions.
Andrea A Monnig et al.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 21(5), 484-495 (2012-02-10)
To review and summarize the human and veterinary literature regarding stress-related mucosal disease (SRMD) pathogenesis, patient risk factors, and therapeutic options for prophylaxis and treatment. SRMD is a common sequela of critical illness in human patients. Development of SRMD results
M R Chruscielewska-Kiliszek et al.
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 15(1), e48-e55 (2012-09-26)
Chronic radiation proctitis is a long-term complication of radiation therapy for pelvic malignancy. The aim of this study was to compare the efficacy and safety of two treatment regimens, sucralfate or placebo, following argon plasma coagulation (APC) for chronic haemorrhagic
Abdulkerim Temiz et al.
Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES, 17(2), 173-176 (2011-06-07)
Solitary rectal ulcer causing lower gastrointestinal bleeding is extremely rare in children. Rare presentation, non-specific symptoms, insufficient experience, and characteristics mimicking other rectal diseases may cause misdiagnosis or delay of diagnosis in some pediatric patients. Here, we report a 10-year-old
Susanne C Diesner et al.
Wiener medizinische Wochenschrift (1946), 162(23-24), 513-518 (2012-11-20)
True food allergens are considered as digestion stable proteins, which are absorbed through the gastrointestinal epithelium in an intact form leading to sensitization and causing systemic symptoms. According to classifications, allergens, which are digestion-labile, cause local symptoms by their cross-reactivity
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