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RES1520C-A7

L-Cystine

Synonym(s):

L-Cystine, (R,R)-3,3′-Dithiobis(2-aminopropionic acid)

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About This Item

Linear Formula:
[-SCH2CH(NH2)CO2H]2
CAS Number:
56-89-3
Molecular Weight:
240.30
EC Number:
200-296-3
UNSPSC Code:
12352200
NACRES:
NA.21
Beilstein/REAXYS Number:
1728094
MDL number:
MFCD00064228

Key Documents

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InChI

1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1

InChI key

LEVWYRKDKASIDU-IMJSIDKUSA-N

SMILES string

N[C@@H](CSSC[C@H](N)C(O)=O)C(O)=O

biological source

plant

assay

98.5-101.0% dry basis

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

mp

>240 °C (dec.) (lit.)

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity; tested

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General description

To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.

Application

L-Cystine is a sulfur containing non-essential amino acid. It is used as a cell culture media component and raw material for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Packaging

Product is available in the following package sizes:
RES1520C-A701X: 100 gm container
RES1520C-A702X: 1 kg container
RES1520C-A704X: 10 kg container
RES1520C-A705X: 25 kg container

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
CDBF8578
CDBF7319
CDBF7318
CDBF5618
CDBF5617

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Anne C Conibear et al.
The Journal of biological chemistry, 288(15), 10830-10840 (2013-02-23)
θ-Defensins are ribosomally synthesized cyclic peptides found in the leukocytes of some primate species and have promising applications as antimicrobial agents and scaffolds for peptide drugs. The cyclic cystine ladder motif, comprising a cyclic peptide backbone and three parallel disulfide
Jan Lewerenz et al.
Antioxidants & redox signaling, 18(5), 522-555 (2012-06-07)
The antiporter system x(c)(-) imports the amino acid cystine, the oxidized form of cysteine, into cells with a 1:1 counter-transport of glutamate. It is composed of a light chain, xCT, and a heavy chain, 4F2 heavy chain (4F2hc), and, thus
Arisa Higa et al.
Molecular and cellular biology, 34(10), 1839-1849 (2014-03-19)
ATF6α, a membrane-anchored transcription factor from the endoplasmic reticulum (ER) that modulates the cellular response to stress as an effector of the unfolded-protein response (UPR), is a key player in the development of tumors of different origin. ATF6α activation has
Philip J Hogg
Nature reviews. Cancer, 13(6), 425-431 (2013-05-11)
Protein action in nature is generally controlled by the amount of protein produced and by chemical modification of the protein, and both are often perturbed in cancer. The amino acid side chains and the peptide and disulphide bonds that bind
Serge-George Rosolen et al.
Advances in experimental medicine and biology, 775, 145-154 (2013-02-09)
In the 70s, the amino acid taurine was found essential for photoreceptor survival. Recently, we found that taurine depletion can also trigger retinal ganglion cell degeneration both in vitro and in vivo. Therefore, evaluation of taurine levels could be a
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