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RES0197M-A7

SAFC

MOPS sodium salt

Pharma Manufacturing

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Synonym(s):
3-(N-Morpholino)propanesulfonic acid sodium salt, 4-Morpholinepropanesulfonic acid sodium salt
Empirical Formula (Hill Notation):
C7H14NNaO4S
CAS Number:
71119-22-7
Molecular Weight:
231.25
MDL number:
MFCD00064350
UNSPSC Code:
12352200
NACRES:
NA.21

biological source

synthetic

Quality Level

400

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

Endotoxin and microbial, tested

useful pH range

6.5-7.9

pKa (25 °C)

7.2

suitability

suitable for manufacturing use

foreign activity

Cytotoxicity, DNase, NICKase, RNase, and Protease; tested

SMILES string

[Na+].[O-]S(=O)(=O)CCCN1CCOCC1

InChI

1S/C7H15NO4S.Na/c9-13(10,11)7-1-2-8-3-5-12-6-4-8;/h1-7H2,(H,9,10,11);/q;+1/p-1

InChI key

MWEMXEWFLIDTSJ-UHFFFAOYSA-M

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General description

Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Application

MOPS Sodium is a biological buffer also referred to as a “Propane Sultone” buffer. The pKa of MOPS Sodium is 7.01 which make it an ideal candidate for medias and protein based buffer formulations to maintain a stable environment in solution. MOPS Sodium is considered to be non-toxic to culture cell lines and provides high solution clarity.

MOPS Sodium is used in cell culture media, biopharmaceutical buffer formulations both upstream and downstream and diagnostic reagents. MOPS based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components. MOPSO based buffers have been described for fixation of cells from urine samples.

Packaging

Product is available in the following package sizes:
RES0197M-A701X: 100g container
RES0197M-A702X 1kg container
RES0197M-A704X: 10kg container
RES0197M-A705X: 25kg container

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

replaced by

Product No.
Description
Pricing

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Ying Hou et al.
Biotechnology progress, 31(4), 974-982 (2015-05-29)
Protein A chromatography is widely employed for the capture and purification of monoclonal antibodies (mAbs). Because of the high cost of protein A resins, there is a significant economic driving force to seek new downstream processing strategies. Membrane chromatography has

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