RES0114M-A7
MES sodium salt
Synonym(s):
2-(N-Morpholino)ethanesulfonic acid sodium salt, 4-Morpholineethanesulfonic acid sodium salt
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About This Item
Empirical Formula (Hill Notation):
C6H12NNaO4S
CAS Number:
Molecular Weight:
217.22
EC Number:
275-203-2
UNSPSC Code:
12161700
NACRES:
NA.21
Beilstein/REAXYS Number:
3765682
MDL number:
InChI
1S/C6H13NO4S.Na/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);/q;+1/p-1
InChI key
IRHWMYKYLWNHTL-UHFFFAOYSA-M
SMILES string
[Na+].[O-]S(=O)(=O)CCN1CCOCC1
biological source
synthetic
form
powder
technique(s)
cell culture | mammalian: suitable
impurities
Endotoxin and microbial, tested
Quality Level
useful pH range
5.5-6.7
pKa
6.1
suitability
suitable for manufacturing use
foreign activity
Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
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General description
Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.
M-Clarity Program
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.
Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
M-Clarity Program
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.
Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
Application
MES Sodium is a biological buffer often referred to as a “Good′s” buffer. The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES Sodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity.
MES Sodium is used in cell culture media, biopharmaceutical buffer formulations both upstream and downstream and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.
MES Sodium is used in cell culture media, biopharmaceutical buffer formulations both upstream and downstream and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins and blood components.
Packaging
Product is available in the following package sizes:
RES0114M-A701X: 100g container
RES0114M-A702X 1kg container
RES0114M-A704X: 10kg container
RES0114M-A705X: 25kg container
RES0114M-A701X: 100g container
RES0114M-A702X 1kg container
RES0114M-A704X: 10kg container
RES0114M-A705X: 25kg container
Legal Information
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Christian Engelbrekt et al.
Chemphyschem : a European journal of chemical physics and physical chemistry, 11(13), 2844-2853 (2010-08-18)
Monodisperse platinum nanoparticles (PtNPs) were synthesized by a green recipe. Glucose serves as a reducing agent and starch as a stabilization agent to protect the freshly formed PtNP cores in buffered aqueous solutions. Among the ten buffers studied, 2-(N-morpholino)ethanesulfonic acid
Ekta G Ahuja et al.
Acta crystallographica. Section D, Biological crystallography, 60(Pt 6), 1129-1131 (2004-05-26)
Phenazines are broad-spectrum antibiotic metabolites produced by organisms such as Pseudomonas and Streptomyces. Phenazines have been shown to enhance microbial competitiveness and the pathogenic potential of the organisms that synthesize them. PhzA (163 residues, approximate molecular weight 18.7 kDa) is
Kefang Xie et al.
Acta crystallographica. Section D, Biological crystallography, 61(Pt 10), 1386-1394 (2005-10-06)
The NNA7 Fab antibody fragment recognizes the human N-type blood-group antigen comprised of the N-terminal glycopeptide of glycophorin A (GPA). A mutant form of this Fab fragment, NNA7-G91S, exhibits markedly reduced antigen binding. To provide insight into how these Fab
Pasi S Vuorinen et al.
Journal of chromatography. A, 990(1-2), 45-52 (2003-04-11)
A contactless conductivity detector integrated into the capillary cassette of Agilent (3D)CE equipment is described. The detector is user-friendly, compact and easily modified. The UV detector of the (3D)CE equipment is available parallel with the contactless conductivity detector increasing the
Taras P Pasternak et al.
Plant physiology, 129(4), 1807-1819 (2002-08-15)
Culturing leaf protoplast-derived cells of the embryogenic alfalfa (Medicago sativa subsp. varia A2) genotype in the presence of low (1 microM) or high (10 microM) 2, 4-dichlorophenoxyacetic acid (2,4-D) concentrations results in different cell types. Cells exposed to high 2,4-D
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