RES0113M-A7
MES monohydrate
Synonym(s):
2-(N-Morpholino)ethanesulfonic acid, 4-Morpholineethanesulfonic acid monohydrate
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About This Item
Linear Formula:
C6H13NO4S · H2O
CAS Number:
Molecular Weight:
213.25
EC Number:
224-632-3
UNSPSC Code:
12161700
NACRES:
NA.21
Beilstein/REAXYS Number:
6350956
MDL number:
form
powder
InChI key
MIIIXQJBDGSIKL-UHFFFAOYSA-N
InChI
1S/C6H13NO4S.H2O/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);1H2
SMILES string
O.OS(=O)(=O)CCN1CCOCC1
biological source
synthetic
technique(s)
cell culture | mammalian: suitable
impurities
Endotoxin, microbial, and trace metals, tested
useful pH range
5.5-6.7
pKa (25 °C)
6.1
mp
>300 °C (lit.)
suitability
suitable for manufacturing use
foreign activity
Cytotoxicity, DNase, NICKase, RNase, and Protease; tested
Quality Level
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Application
MES is a biological buffer often referred to as a “Good′s” buffer .The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES is considered to be non-toxic to culture cell lines, highly water soluble and provides high solution clarity.
MES is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream), and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors.
MES is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream), and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors.
General description
Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.
M-Clarity Program
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.
Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
M-Clarity Program
Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.
Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.
Packaging
Product is available in the following package sizes:
RES0113M-A701X: 100g container
RES0113M-A703X: 5kg container
RES0113M-A705X: 25kg container
RES0113M-A706X: 50kg container
RES0113M-A701X: 100g container
RES0113M-A703X: 5kg container
RES0113M-A705X: 25kg container
RES0113M-A706X: 50kg container
Legal Information
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
11 - Combustible Solids
wgk
WGK 3
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