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Key Documents

Safety Information

RAB1074

Sigma-Aldrich

Human PGRN ELISA Kit

for cell culture supernatants, plasma, and serum samples

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5 MG
¥2,225.57
25 MG
¥10,451.30

¥2,225.57

List Price¥2,749.22Save 19%

Please contact Customer Service for Availability


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5 MG
¥2,225.57
25 MG
¥10,451.30

About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

¥2,225.57

List Price¥2,749.22Save 19%

Please contact Customer Service for Availability

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type serum sample(s)
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.1 ng/ml

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... GRN(2896)

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This Item
A6150A2221SRP6312
biological source

human plasma

biological source

human plasma

biological source

human plasma

biological source

human

assay

≥70% protein basis (biuret)

assay

-

assay

≥95% (SDS-PAGE)

assay

≥95% (SDS-PAGE)

Gene Information

human ... ELA2(1991), SERPINA1(5265)

Gene Information

human ... ELA2(1991), ELANE(1991), SERPINA1(5265)

Gene Information

human ... SERPINC1(462)

Gene Information

human ... Serpin A1(5265)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

form

salt-free, lyophilized powder

form

salt-free, lyophilized powder

form

lyophilized powder

form

lyophilized

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

General description

This ELISA antibody pair detects human PGRN. Other species are not determined.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Pictograms

Corrosion

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Anfei Huang et al.
JCI insight, 4(17) (2019-09-06)
`NK cell-mediated regulation of antigen-specific T cells can contribute to and exacerbate chronic viral infection, but the protective mechanisms against NK cell-mediated attack on T cell immunity are poorly understood. Here, we show that progranulin (PGRN) can reduce NK cell
Yanqing Li et al.
Journal of neuropathology and experimental neurology, 78(5), 406-415 (2019-04-03)
Progranulin (PGRN) plays critical roles in inflammation, tumorigenesis, and neurodegeneration. PGRN levels in blood and cerebrospinal fluid (CSF) are being increasingly investigated as potential biomarkers for these disorders. However, the value of CSF PGRN as a biomarker has been limited
Yingguang Han et al.
Inflammation, 40(3), 946-955 (2017-03-02)
The aim of this study was to investigate progranulin (PGRN) expression and its effect in cartilage degradation and in the pathogenesis of osteonecrosis of the femoral head (ONFH). Cartilage specimens were obtained from ONFH and FNF patients and PGRN expression
Kai-Di Yang et al.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 39(12), 2405-2414 (2020-07-29)
Neonatal early-onset sepsis (EOS) is associated with high morbidity and mortality. Accurate early diagnosis is crucial for prompt treatment and a better clinical outcome. We aimed to identify new biomarkers for the diagnosis of EOS. A total of 152 neonates
Fengyun Wang et al.
Disease markers, 2018, 3729402-3729402 (2018-08-29)
Progranulin (PGRN), a novel peptide that has recently emerged as an important regulatory adipokine, is relevant to energy homeostasis and obesity in animals and adult humans. Little is known about its roles in children. The aim of the current study

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