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Merck
CN

RAB1052

Human GHRL/Ghrelin ELISA Kit

for cell culture supernatants, plasma, and serum samples

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About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
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Product Name

Human GHRL/Ghrelin ELISA Kit, for cell culture supernatants, plasma, and serum samples

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type plasma
sample type serum sample(s)
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... GHRL(51738)

Other Notes

A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.

Biochem/physiol Actions

The peptide ghrelin, one of the cleavage products of prepropeptide produced from the GHRL (growth hormone-releasing peptide) gene, functions in stimulating food intake and controlling energy balance. It has potent stimulating effects on the secretion of growth hormone. GHRL serves as an endogenous ligand for the growth hormone secretagogue receptor 1α (GHSR 1α). The protein regulates body weight on long-term and appetite on short-term. Preadipocyte differentiation stimulated by ghrelin is found to increase BMI and negatively regulate the anorexigenic effect of leptin. Polymorphism in the GHRL gene is linked to variations in blood pressure, high-density lipoproteins, low-density lipoproteins, serum cholesterol, blood glucose and metabolic syndrome.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.

General description

This ELISA antibody pair detects Human Ghrelin (GHRL)

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Zachary A Sorrentino et al.
Cureus, 12(11), e11409-e11409 (2020-11-17)
Despite the reduced caloric content of artificially sweetened beverages (ASBs) relative to those sweetened with sucrose, consumption of ASBs fail to consistently decrease the risk of obesity and associated diseases. This failure may be due to the inability of ASBs
Zhi Jiang et al.
World journal of gastroenterology, 23(16), 2987-2994 (2017-05-20)
To investigate the effects of Xiangbin prescription (XBP), a Chinese herbal concoction, on gastrointestinal motility. Forty healthy volunteers were recruited for this randomized controlled trial of XBP. Antroduodenojejunal manometry was used to monitor gastrointestinal motility in these subjects. After the
Zeynep Canan Özdemir et al.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 33(9), 1486-1491 (2018-09-07)
Objectives: To investigate the association of ghrelin, leptin, and insulin levels in the umbilical cord blood of the preterm and term infants with anthropometric measurements and glucose metabolism.Methods: Sixty-nine infants who were born between November 2004 and June 2005 were
Maria Poessel et al.
Nutrients, 12(8) (2020-07-30)
The worldwide obesity epidemic is a major health problem driven by the modern food environment. Recently, it has been shown that smell perception plays a key role in eating behavior and is altered in obesity. However, the underlying mechanisms of
Zudin A Puthucheary et al.
Thorax, 73(10), 926-935 (2018-07-08)
To characterise the sketetal muscle metabolic phenotype during early critical illness. Vastus lateralis muscle biopsies and serum samples (days 1 and 7) were obtained from 63 intensive care patients (59% male, 54.7±18.0 years, Acute Physiology and Chronic Health Evaluation II

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