RAB0857
Mouse Ptx3 / Pentraxin-related Protein PTX3 ELISA Kit
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
Recommended Products
species reactivity
mouse
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type plasma
sample type serum
sample type cell culture supernatant(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.6 ng/mL
standard curve range: 0.614-150 ng/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
mouse ... Ptx3(19288)
General description
The antibody pair provided in this kit recognizes mouse Pentraxin-related Protein PTX3 / Pentraxin 3.
The pentraxin3 (PTX3) gene encodes for a long PTX3 protein, an acute-phase protein. PTX3 protein is a member of the pentraxin family and is present in several cells and tissues. It is observed during brain inflammatory response and seizure. PTX3 plays a role in angiogenesis, tissue remodeling, and female fertility. It promotes phagocytosis of pathogen and inhibits the phagocytosis of apoptotic cells. The antibody pair provided in this kit recognizes mouse pentraxin-related protein PTX3 / pentraxin 3.
Application
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Ning Xu et al.
Medicine, 99(3), e18740-e18740 (2020-02-06)
To investigate the interaction between the single nucleotide polymorphism of the 3' untranslated region (3'UTR) of the pentraxin 3 (PTX3) gene, as well as environmental factors and the preeclampsia risk in a Chinese Han population.Sanger sequencing was used to analyze
Hyejin Jeon et al.
Journal of neuroimmunology, 229(1-2), 63-72 (2010-08-03)
Microglia, as the phagocytes of the central nervous system, play an important role in the recognition, engulfment, and clearance of apoptotic cells and invading microbes. Proteins secreted from activated glial cells may affect microglial phagocytic activity. Secreted proteins of mixed
H Li et al.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 25(4), 504-510 (2018-07-03)
Pentraxin 3 (PTX3) contributes to resistance to Aspergillus infections. This study aimed to evaluate the presence of PTX3 in bronchoalveolar lavage fluid (BALF) and plasma in non-neutropenic patients with pulmonary aspergillosis. BALF (n = 211) and plasma samples (n = 307) were collected from
Jiale Diao et al.
Endocrine, 70(1), 78-84 (2020-04-18)
Transforming growth factor-β (TGF-β), recognized as a crucial factor in regulating fibrosis and tissue remodeling, plays a role in thyroid-associated ophthalmopathy (TAO). Pentraxin-3 (PTX3), a member of pentraxins, was recently implicated in many autoimmune and fibrotic diseases. Thus, we hypothesize
Local complement activation is associated with primary graft dysfunction after lung transplantation.
Hrishikesh S Kulkarni et al.
JCI insight, 5(17) (2020-08-05)
BACKGROUNDThe complement system plays a key role in host defense but is activated by ischemia/reperfusion injury (IRI). Primary graft dysfunction (PGD) is a form of acute lung injury occurring predominantly due to IRI, which worsens survival after lung transplantation (LTx).
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