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Key Documents

Safety Information

RAB0797

Sigma-Aldrich

Mouse IgA ELISA Kit

Synonym(s):

IgA, Immunoglobulin A

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32
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species reactivity

mouse

technique(s)

ELISA: suitable

assay range

inter-assay cv: <10%
intra-assay cv: <12%

shipped in

wet ice

storage temp.

−20°C

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Bovine Serum Albumin &#8805;98.5%, New Zealand origin

BSAVRO

Bovine Serum Albumin

Bovine Serum Albumin Fraction V pack of 100&#160;g

810533

Bovine Serum Albumin Fraction V

Bovine Serum Albumin Fraction V pack of 10&#160;g

81053N

Bovine Serum Albumin Fraction V

Bovine Serum Albumin Fraction V pack of 5&#160;kg

810535

Bovine Serum Albumin Fraction V

assay

≥98.5%

assay

≥98% (purity)

assay

≥98% (purity)

assay

≥98% (purity)

technique(s)

ELISA: suitable, western blot: suitable, Southern blotting: suitable

technique(s)

blood typing: suitable ( )

technique(s)

blood typing: suitable ( )

technique(s)

blood typing: suitable ( )

origin

New Zealand origin

origin

USA origin

origin

USA origin

origin

USA origin

biological source

bovine

biological source

bovine serum

biological source

bovine serum

biological source

bovine serum

Quality Level

100

Quality Level

300

Quality Level

300

Quality Level

300

form

lyophilized

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

General description

The antibody pair provided in this kit recognizes Mouse IgA.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Immunoglobulin A (IgA) is majorly found in the mucosal secretions. IgA exists as two subclasses, IgA1 and IgA2. IgA is a dimer in animals, but a monomer in humans. IgA interacts with the Fc fragment of IgA receptor (FCAR) to elicit immune response against inhaled pathogens.[1] Secretory IgA (S-IgA) produced by B1 lymphocytes triggers phagocytosis and leucocyte respiratory burst.[2] S-IgA exists as a polymer and is crucial for primary defense. The high levels of IgA in human milk and colostrum may provide immune protection to infants. Deficiency of IgA leads to increased susceptibility to infections. High levels of IgA in kidney is present in IgA nephropathy and IgA myeloma.[3] Autoantibodies of IgA is present in celiac disease.[4]

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
  • RABSTOP3ELISA Stop Solution (Item I)
  • RABWASH420X Wash Buffer (Item B)

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    0516K0548
    1228I0548
    1130I0548
    1214I0548
    1026I0548

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    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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    Find documentation for the products that you have recently purchased in the Document Library.

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    Immunoglobulin A (IgA) deficiency and alternative celiac disease-associated antibodies in sera submitted to a reference laboratory for endomysial IgA testing
    Prince HE, et al.
    Clinical and Diagnostic Laboratory Immunology, 7(2), 192-196 (2000)
    Anna-Carin Lundell et al.
    Scientific reports, 7(1), 15503-15503 (2017-11-16)
    Boys present with higher proportions of immature/naïve CD5
    T Gupalova et al.
    PloS one, 13(5), e0196564-e0196564 (2018-05-05)
    Streptococcus agalactiae, or group B streptococcus (GBS), is an important pathogen as it is the leading cause of neonatal deaths due to sepsis, meningitis or bacterial pneumonia. Although the development of an effective and safe GBS vaccine is on the
    Yiran Wang et al.
    Molecular immunology, 112, 305-311 (2019-06-24)
    The pathophysiology of type II diabetes (T2D) in patients with normal body-mass index (BMI) remains unclear. In this study, we investigated the circulating CD4+CXCR5+ T cells in lean T2D patients. Compared with age-, gender-, and BMI-matched healthy controls, the lean
    Liqing Huang et al.
    Probiotics and antimicrobial proteins, 11(3), 946-956 (2018-06-28)
    The effects of Enterococcus faecium on growth, intestinal barrier function, and immune response in Escherichia coli O78-challenged broiler chickens were investigated. Three hundred eight 1-day-old Ross male chickens were randomly assigned into three treatment groups: negative control (C), E. coli
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