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Safety Information

RAB0319

Sigma-Aldrich

Human IL-8 / CXCL8 ELISA Kit

for serum, plasma, cell culture supernatant and urine

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1 G
¥2,019.39
5 G
¥9,729.92

¥2,019.39

Available to ship on2025年4月27日Details

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1 G
¥2,019.39
5 G
¥9,729.92

About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

¥2,019.39

Available to ship on2025年4月27日Details

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type serum
sample type plasma
sample type cell culture supernatant(s)

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... IL8(3576)

General description

Interleukin-8 (IL-8)/CXCL8 is an important chemoattractant cytokine and activator of neutrophils. It is liberated from endothelial cells, gingival fibroblasts, neutrophils, monocytes and phagocytes in the gingival crevice.[1] IL-8 belongs to the CXC subfamily. This gene is located on human chromosome 4q13.3.[2]

Immunogen

Recombinant Human IL-8

Application

Human IL-8 /CXCL8 ELISA Kit has been used:
  • to quantify IL?8 from A549 cell culture medium[3]
  • in quantitative measurement of IL-8 from cell culture supernatant[4]
  • in supernates of acute lung infection model (ALIM)[5]

Biochem/physiol Actions

Interleukin-8 (IL-8)/CXCL8 participates in the progression of peripheral muscle weakness in individuals with COPD (chronic obstructive pulmonary disease).[6] It helps in the transport of neutrophils across endothelium, pulmonary epithelium and fibroblasts.[7]

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)
  • RABSTOP3ELISA Stop Solution (Item I)
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
  • RABWASH420X Wash Buffer (Item B)

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Regulatory Information

常规特殊物品
  • Specification Sheet

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    1025J0143
    0824J0143
    0816J0143
    0829J0143
    0803J0143

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    Find documentation for the products that you have recently purchased in the Document Library.

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    Association between interleukin-8 levels and chronic periodontal disease: A PRISMA-compliant systematic review and meta-analysis
    Finoti LS, et al.
    Medicine, 96(22) (2017)
    Effect and mechanism of calpains on pediatric lobar pneumonia.
    Yin G, et. al.
    Bioengineered, 8, 374-374 (2017)
    Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases
    Mukaida N
    American Journal of Physiology. Lung Cellular and Molecular Physiology (2003)
    Effects of rilpivirine, 17 beta-estradiol and beta-naphthoflavone on the inflammatory status of release of adipocytokines in 3T3-L1 adipocytes in vitro
    Behl S, et al.
    Molecular Biology Reports, 46(3), 2643-2655 (2019)
    Alexandra Gkourogianni et al.
    PloS one, 9(4), e94001-e94001 (2014-04-15)
    There have been increasing indications about an epigenetically-based elevated predisposition of assisted reproductive technology (ART) offspring to insulin resistance, which can lead to an unfavorable cardio-metabolic profile in adult life. However, the relevant long-term systematic molecular studies are limited, especially
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