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Merck
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RAB0312

Rat Interleukin-6 ELISA Kit

for for cell lysate and tissue lysate

Synonym(s):

IL-6, Interleukin-6 

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About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
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Product Name

Rat Interleukin-6 ELISA Kit, for for cell lysate and tissue lysate

species reactivity

rat

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type tissue lysate
sample type cell lysate

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 15 pg/mL
standard curve range: 40.96-10000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

rat ... Il6(24498)

General description

The Rat IL-6 ELSA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Rat IL-6 cell lysate and tissue lysate.

Immunogen

Recombinant Rat IL-6

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Rat Interleukin-6 ELISA Kit has been used to determine the plasma level of interleukin-6 (IL-6) via ELISA.

Biochem/physiol Actions

Interleukin-6 (IL-6) acts as a neuromodulation factor. IL-6 has two signalling pathways, known as classic signalling pathway and trans-signalling pathway. It has a neuroprotective role in ischemic stroke, by activating IL-6/interleukin 6 receptor (IL-6R)/signal transducers and activators of transcription 3 (STAT3) signalling pathway. IL-6 is a multifunctional cytokine, which is implicated in acute inflammation. IL-6 is associated with SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome.

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

Regulatory Information

含少量动物源组分生物产品
常规特殊物品
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Thomas A Rasmussen et al.
The lancet. HIV, 5(5), e221-e230 (2018-04-13)
Whether ongoing virus replication occurs in HIV-infected individuals on antiretroviral therapy (ART) is unclear; therefore, whether residual virus replication is a barrier to achieving a cure for HIV is also unknown. We aimed to establish whether ART intensification with dolutegravir
Celestino Sardu et al.
Journal of the American Heart Association, 9(17), e016948-e016948 (2020-07-08)
BACKGROUND Coronavirus disease 2019 (COVID-19) is the cause of a pandemic disease, with severe acute respiratory syndrome by binding target epithelial lung cells through angiotensin-converting enzyme 2 in humans. Thus, patients with hypertension with COVID-19 could have worse prognosis. Indeed
Mike Recher et al.
NPJ vaccines, 3, 17-17 (2018-05-26)
Pneumococcal conjugate vaccine (PCV) is recommended for adults with chronic disease. Extensive limb swelling (ELS) is an acute vigorous local inflammatory reaction following vaccination. Predisposing immune system correlates and the influence of ELS on vaccine responses are not known. Here
Effects of interleukin-6 and IL-6/AMPK signaling pathway on mitochondrial biogenesis and astrocytes viability under experimental septic condition
Chen XL, et al.
International Immunopharmacology, 59, 287-294 (2018)
Interleukin-6 RNA knockdown ameliorates acute lung injury induced by intestinal ischemia reperfusion in rats by upregulating interleukin-10 expression
Yuan B, et al.
Molecular Medicine Reports, 16(3), 2529-2537 (2017)

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