RAB0307
Human IL-6 ELISA Kit
for cell and tissue lysates
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Synonym(s):
B-cell stimulatory factor 2, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, IL-6
UNSPSC Code:
41116158
NACRES:
NA.32
Recommended Products
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type tissue lysate
sample type cell lysate
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 3 pg/mL
standard curve range: 1.37-1000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... IL6(3569)
General description
The Human IL-6 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human IL-6 cell lysate and tissue lysate.
Immunogen
Recombinant Human IL-6
Application
For research use only. Not for use in diagnostic procedures.
Human IL-6 ELISA kit has been used for determining the levels of IL-6 in human cells.
Human IL-6 ELISA kit has been used for determining the levels of IL-6 in human cells.
Biochem/physiol Actions
IL-6 (interleukin 6) is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 is associated with various autoimmune and inflammatory diseases. High levels of IL-6 are present in the synovial fluid from rheumatoid arthritis patients. It is also linked with chronic inflammatory proliferative disease and B cell malignancy, Castleman′s disease, and plasmacytoma/multiple myeloma.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit Components Also Available Separately
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Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
WGK
WGK 3
Regulatory Information
常规特殊物品
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Gaohua Han et al.
Oncology letters, 18(1), 321-329 (2019-07-11)
The present study evaluated the role of annexin A1 (ANXA1) in the treatment of acute radiation-induced lung injury (RILI) and investigated the mechanism of its action. The expression of ANXA1, interleukin-6 (IL-6) and myeloperoxidase (MPO) in the plasma of patients
Hongjun Yang
American journal of translational research, 13(7), 8391-8396 (2021-08-12)
To explore the cytokine expression level of interstitial lung disease in primary Sjogren's syndrome (ILD-pSS) patients and its clinical significance. 50 pSS patients in our hospital from Jan 2017 to Dec 2019 were selected as pSS group and separated into
Interleukin-6: discovery of a pleiotropic cytokine.
Kishimoto T
Arthritis Research & Therapy, 8, S2-S2 (2006)
Suresh Gopi Kalathil et al.
American journal of respiratory and critical care medicine, 190(1), 40-50 (2014-05-16)
Previous studies from our laboratory have shown that peripheral blood mononuclear cells (PBMCs) from patients with chronic obstructive pulmonary disease (COPD) prone to exacerbations with nontypeable Haemophilus influenzae have impaired responses to lipoprotein P6. We hypothesized that an underlying immunosuppressive
Marine Gilabert et al.
Journal of cellular physiology, 229(10), 1437-1443 (2014-03-22)
Cancer cachexia syndrome is observed in 80% of patients with advanced-stage cancer, and it is one of the most frequent causes of death. Severe wasting accounts for more than 80% in patients with advanced pancreatic cancer. Here we wanted to
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