RAB0160
Human EGFR / ErbB1 ELISA Kit
for serum, plasma, cell culture supernatants and urine
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About This Item
NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... EGFR(1965)
Input:
sample type urine
sample type cell culture supernatant(s)
sample type plasma
sample type serum
sample type cell culture supernatant(s)
sample type plasma
sample type serum
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable, capture ELISA: suitable
input
sample type urine
sample type cell culture supernatant(s)
sample type plasma
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 pg/mL
standard curve range: 2.74-2000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... EGFR(1965)
General description
Epidermal growth factor receptor (EGFR) is a member of the epidermal growth factor receptor tyrosine kinase (RTK) family. It is a single-chain transmembrane glycoprotein. EGFR comprises an extracellular ligand-binding ectodomain, a short juxtamembrane section, a transmembrane domain, a tyrosine kinase domain, tyrosine-containing C-terminal tail. Overexpression of EGFR is observed in breast cancer cells.
Immunogen
Recombinant Human EGFR
Application
Human EGFR / ErbB1 ELISA Kit has been used in the estimation of epidermal growth factor receptors (EGFR) from human epithelial cells. It has also been used in the detection of EGFR from patient plasma/serum and exosomes isolated from human prostate cancer cells LNCaP xenografts.
Other Notes
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
Kit Components Also Available Separately
Product No.
Description
SDS
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
Storage Class
8A - Combustible corrosive hazardous materials
Regulatory Information
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Chung-Ming Huang et al.
PloS one, 12(7), e0180604-e0180604 (2017-07-13)
We have previously described the association of rheumatoid arthritis (RA) prevalence and two epidermal growth factor receptor (EGFR) SNPs (rs17337023 and rs2227983) among the Taiwanese population. This present study aimed to elucidate whether the SNPs can alter the expression of
M J Wieduwilt et al.
Cellular and molecular life sciences : CMLS, 65(10), 1566-1584 (2008-02-09)
The epidermal growth factor family of receptor tyrosine kinases (ErbBs) plays essential roles in regulating cell proliferation, survival, differentiation and migration. The ErbB receptors carry out both redundant and restricted functions in mammalian development and in the maintenance of tissues
Mónika Korodi et al.
Journal of immunological methods, 483, 112812-112812 (2020-06-23)
Covalent immobilization of antibodies to protein G beads is a basic molecular biology method, although the beads present poor recovery results. Our aim was to reuse the immobilized antibody-protein G complex on a very small scale, therefore we optimized the
Yi Zhao et al.
Cancer research, 80(11), 2217-2229 (2020-03-21)
Stemness and epithelial-mesenchymal transition (EMT) are two fundamental characteristics of metastasis that are controlled by diverse regulatory factors, including transcription factors. Compared with other subtypes of breast cancer, basal-type or triple-negative breast cancer (TNBC) has high frequencies of tumor relapse.
Jiao-Jiao Yu et al.
Nature communications, 11(1), 3660-3660 (2020-07-23)
High expression or aberrant activation of epidermal growth factor receptor (EGFR) is related to tumor progression and therapy resistance across cancer types, including non-small cell lung cancer (NSCLC). EGFR tyrosine kinase inhibitors (TKIs) are first-line therapy for NSCLC. However, patients
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