RAB0017
Human ANGPTL4 ELISA Kit
for serum, plasma and cell culture supernatants
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About This Item
UNSPSC Code:
41116158
NACRES:
NA.32
Recommended Products
species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
capture ELISA: suitable
input
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 20 pg/mL
standard curve range: 27.4-20000 pg/mL
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... ANGPTL4(51378)
General description
The Human ANGPTL4 (Angiopoietin-like 4) ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human ANGPTL4 in serum, plasma and cell culture supernatants.
Immunogen
Recombinant Human Angiopoietin-like 4
Application
For research use only. Not for use in diagnostic procedures.
Human angiopoietin-like protein 4 (ANGPTL4) ELISA kit has been used for the quantitative measurement of ANGPTL4 in serum and urinary samples.
Human angiopoietin-like protein 4 (ANGPTL4) ELISA kit has been used for the quantitative measurement of ANGPTL4 in serum and urinary samples.
Biochem/physiol Actions
Angiopoietin like 4 (ANGPTL4) possesses a characteristic large fibrinogen/angiopoietin like domain. It inhibits lipoprotein lipase and thus increases plasma triglyceride levels. The protein regulates the uptake of free fatty acids in fasting and fed conditions. ANGPTL4 is also involved in homeostasis, insulin sensitivity and apoptosis of vascular endothelial cells. It has been reported to have a role in atherosclerosis and may modulate inflammatory responses.
Other Notes
A sample Certificate of Analysis is available for this product.
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Please type the word sample in the text box provided for lot number.
Kit Components Also Available Separately
Product No.
Description
SDS
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Met. Corr. 1
Storage Class Code
8A - Combustible corrosive hazardous materials
Regulatory Information
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Gabriel Cara-Fuentes et al.
PloS one, 12(4), e0176198-e0176198 (2017-04-26)
Minimal Change Disease (MCD) is the most common type of nephrotic syndrome in children. Angiopoietin-like-4 (Angplt4) has been proposed as mediator of proteinuria in MCD. The aim of this study was to evaluate the role of Angptl4 as a biomarker
Viktoria Gusarova et al.
Nature communications, 9(1), 2252-2252 (2018-06-15)
Angiopoietin-like 4 (ANGPTL4) is an endogenous inhibitor of lipoprotein lipase that modulates lipid levels, coronary atherosclerosis risk, and nutrient partitioning. We hypothesize that loss of ANGPTL4 function might improve glucose homeostasis and decrease risk of type 2 diabetes (T2D). We
Serum angiopoietin-like 4 is over-expressed in COPD patients: association with pulmonary function and inflammation.
Wu YQ
European Review for Medical and Pharmacological Sciences (2016)
Angiopoietin-like protein 4 serum levels and gene polymorphisms are associated with large artery atherosclerotic stroke.
He XW
Journal of the Neurological Sciences (2016)
İbrahim Aslan et al.
Prostaglandins & other lipid mediators, 128-129, 1-7 (2016-12-28)
This study aimed to determine circulating levels of polyunsaturated fatty acids (PUFAs), secretory phospholipase A2 (sPLA2), lipoprotein lipase (LPL) and measure circulating protein levels of angiopoietin-like protein 3 (ANGPTL3), ANGPTL4, cyclooxygenase-2 (COX-2) and prostaglandin E2 (PGE2) in patients with acne
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