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Merck
CN

RAB0007

Human RAGE / AGER ELISA Kit

for serum, plasma, cell culture supernatant and urine

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About This Item

NACRES:
NA.32
UNSPSC Code:
41116158
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Product Name

Human RAGE / AGER ELISA Kit, for serum, plasma, cell culture supernatant and urine

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type cell culture supernatant(s)
sample type plasma
sample type serum
sample type urine

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 3 pg/mL
standard curve range: 2.06-1500 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... AGER(177)

Application

For research use only. Not for use in diagnostic procedures.

Human RAGE / AGER ELISA kit has been used for the quantitative measurement of RAGE in cerebrospinal fluid.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Advanced glycosylation end-product specific receptor (AGER) or RAGE is part of the immunoglobulin superfamily of cell surface molecules. The soluble form of the protein has a function in the Wnt pathway. RAGE has a role in the development of inflammatory and cellular damage, as well as cellular toxicity. It has been associated with diabetic atherosclerosis. AGER/RAGE also modulates cell proliferation, differentiation and apoptosis.(6}

General description

The Human RAGE ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human RAGE in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human RAGE

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

pictograms

Corrosion

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Warning

hcodes

Hazard Classifications

Met. Corr. 1

Storage Class

8A - Combustible corrosive hazardous materials

Regulatory Information

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An inverse association between serum soluble receptor of advanced glycation end products and hyperandrogenism and potential implication in polycystic ovary syndrome patients
Yu Liao
Reproductive Biology and Endocrinology, 15, 9-9 (2017)
Increase of Soluble RAGE in Cerebrospinal Fluid following Subarachnoid Haemorrhage
Bartosz Sokol
BioMed Research International (2017)
Association of Polymorphisms of the Receptor for Advanced Glycation Endproducts Gene with Schizophrenia in a Han Chinese Population
Jiawu Fu
Biomedical Research, 6379639-6379639 (2017)
Association of RAGE gene Gly82Ser polymorphism with coronary artery disease and ischemic stroke
Wen-Qi Ma
Medicine, 95(49), e5593-e5593 (2016)
Circulating sRAGE in the diagnosis of osteolytic bone metastasis.
Galliera E
Journal of Biological Regulators and Homeostatic Agents, 30(4), 1203-1208 (2016)

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