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Safety Information

RAB0005

Sigma-Aldrich

Human ADIPOQ / Adiponectin ELISA Kit

for serum, plasma, cell culture supernatant and urine

Synonym(s):

Adiponectin, 30 kDa adipocyte complement-related protein, ACDC, ACRP30, ADPN, Adipocyte complement-related 30 kDa protein, Adipocyte, C1q and collagen domain-containing protein, Adipose most abundant gene transcript 1 protein

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.32

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable
capture ELISA: suitable

input

sample type cell culture supernatant(s)
sample type plasma
sample type urine
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 25 pg/mL
standard curve range: 24.69-18000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... ADIPOQ(9370)

General description

The Human Adiponectin ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of human Adiponectin in serum, plasma, cell culture supernatants and urine.

Immunogen

Recombinant Human Adiponectin

Application

For research use only. Not for use in diagnostic procedures.
Human ADIPOQ / Adiponectin ELISA Kit has been used for the measurement of adiponectin in human plasma.
Human ADIPOQ / Adiponectin ELISA Kit has been used in the quantification of leptin and adiponectin from serum and plasma samples.

Biochem/physiol Actions

Adiponectin (ADIPOQ) is an adipocyte specific secreted protein that circulates in the plasma. The protein has a carboxyl-terminal globular domain and an amino-terminal collagen domain. It has anti-atherosclerotic and anti-inflammatory properties. ADIPOQ has a role in physiological processes such as energy homeostasis and obesity. It exhibits anti-diabetic action by interacting with adiponectin receptors, AdipoR1 and AdipoR2. Low levels of adiponectin are also linked with hypertension and dyslipidemia. Mutation in the gene encoding it is linked with risk for endometrial cancer.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDS
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDS
  • RABELADCELISA 1X Assay/Sample Diluent Buffer C (Item L)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Regulatory Information

新产品

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Certificates of Analysis (COA)

Lot/Batch Number
1103J0101
1110J0101
1010J0101
0927J0101
0922J0101

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Yoshimitsu Tanaka et al.
Scientific reports, 9(1), 16-16 (2019-01-11)
Skeletal muscle has remarkable regenerative potential and its decline with aging is suggested to be one of the important causes of loss of muscle mass and quality of life in elderly adults. Metabolic abnormalities such as obesity were linked with
The absorption and metabolism of a single L-menthol oral versus skin
administration: Effects on thermogenesis and metabolic rate
Angelica V
Food And Chemical Toxicology (2015)
Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.
Hotta K
Arteriosclerosis, Thrombosis, and Vascular Biology (2000)
Ioana Hristov et al.
Lipids in health and disease, 18(1), 141-141 (2019-06-14)
The adipocyte expansion is a critical process with implications in the pathogenesis of obesity associated metabolic syndrome. Impaired adipogenesis leads to dysfunctional, hypertrophic adipocytes, local inflammation and peripheric insulin resistance. We assessed the relationship between the adipogenic differentiation capacity of
Genetic architecture of the APM1 gene and its influence on adiponectin plasma levels and parameters of the metabolic syndrome in 1,727 healthy Caucasians.
Heid IM
Diabetes (2006)
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