R7502
Roridin A from Myrothecium sp.
powder, ≥98% (TLC)
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About This Item
Empirical Formula (Hill Notation):
C29H40O9
CAS Number:
Molecular Weight:
532.62
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Recommended Products
Assay
≥98% (TLC)
form
powder
solubility
chloroform: ≥10 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
CC(O)C1OCCC(C)C(O)C(=O)OCC23CCC(C)=CC2OC4CC(OC(=O)\C=C\C=C\1)C3(C)C45CO5
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Oral
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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T S Gu et al.
Biotechnology and applied biochemistry, 13(2), 212-216 (1991-04-01)
In yeasts, growth temperature is known to affect the membrane phospholipid content. The effect of temperature on the growth inhibition of Kluyveromyces marxianus and Saccharomyces cerevisiae by the trichothecene mycotoxins, T-2 toxin and roridin A, was investigated. Examination of EC50
Y Sugita-Konishi et al.
Toxicon : official journal of the International Society on Toxinology, 32(9), 1051-1057 (1994-09-01)
The in vitro effect of macrocyclic trichothecenes, roridin A and verrucarin A, and a non-macrocyclic trichothecene, T-2 toxin, on the concanavalin A-induced murine T-cell blastogenesis was investigated. The macrocyclic trichothecenes inhibited the blastogenesis of both thymocytes and splenocytes, splenocytes being
B B Jarvis et al.
Journal of medicinal chemistry, 27(2), 239-244 (1984-02-01)
Various 8 beta-hydroxy, 16-hydroxy, and 9 beta,10 beta-epoxy derivatives of roridins A and H and verrucarins A and J have been prepared and tested in vivo against P388 mouse leukemia. The 9 beta,10 beta-epoxy derivatives and 16-hydroxy derivatives consistently exhibit
J Y Liu et al.
Journal of applied microbiology, 100(1), 195-202 (2006-01-13)
Fungal infection is still a life-threatening risk for the immunocompromised population such as AIDS patients and those who receive treatments with immunosuppressors and/or frequent administrations of wide-spectrum antibiotics, which inevitably lead to the drug resistance and unbalanced microflora populations. The
Isolation of a mycotoxin (roridin A) from Phomopsis spp.
D Samples et al.
Veterinary and human toxicology, 26(1), 21-23 (1984-02-01)
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