R7502
Roridin A from Myrothecium sp.
powder, ≥98% (TLC)
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About This Item
Empirical Formula (Hill Notation):
C29H40O9
CAS Number:
Molecular Weight:
532.62
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Recommended Products
Assay
≥98% (TLC)
form
powder
solubility
chloroform: ≥10 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
CC(O)C1OCCC(C)C(O)C(=O)OCC23CCC(C)=CC2OC4CC(OC(=O)\C=C\C=C\1)C3(C)C45CO5
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 2 Oral
Storage Class Code
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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B Yagen et al.
Experientia, 43(8), 886-888 (1987-08-15)
Several trichothecene mycotoxins were shown to inhibit the growth of Saccharomyces cerevisiae. This effect was most pronounced with the macrocyclic trichothecenes, especially verrucarin A. Much less growth inhibition was observed with T-2 toxin. Verrucarol, diacetoxyscirpenol, acetyl T-2 toxin, HT-2 toxin
Isolation of a mycotoxin (roridin A) from Phomopsis spp.
D Samples et al.
Veterinary and human toxicology, 26(1), 21-23 (1984-02-01)
J K Bubien et al.
Toxicon : official journal of the International Society on Toxinology, 25(3), 325-331 (1987-01-01)
Intravenous injection of T-2 toxin or roridin-A (2 mg/kg) into pentobarbital-anesthetized (30 mg/kg) dogs produced, respectively, decreased systolic pressure within 30 min and atrio-ventricular block within 60 min. Within 45 +/- 15 min after injection of each toxin heart rate
S C Wilson et al.
International journal of toxicology, 24(3), 181-186 (2005-07-26)
The efficacy of chlorine dioxide (ClO2) in detoxifying two potential bioterrorism agents, the trichothecene mycotoxins verrucarin A and roridin A, was evaluated. In the first experiment, verrucarin A (1, 5, or 10 microg) and roridin A (5 or 10 microg)
J J Pestka et al.
Toxicology letters, 41(3), 215-222 (1988-06-01)
The effect of in vitro exposure to the macrocyclic trichothecenes roridin A and verrucarin A on human lymphocyte transformation was evaluated in the mitogen-induced blastogenesis assay. Both compounds were capable of inhibiting stimulation of B- and T-cell subsets by a
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