R4001
Ribonuclease A-agarose
ammonium sulfate suspension, 400-1,000 units/g agarose (One ml gel will yield 12-30 units)
Synonym(s):
Ribonuclease I, Ribonucleate 3′-pyrimidinooligonucleotidohydrolase
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Specific activity:
400-1,000 units/g agarose (One ml gel will yield 12-30 units)
Biological source:
protein from bovine pancreas
biological source
protein from bovine pancreas
material
beaded agarose
form
ammonium sulfate suspension
specific activity
400-1,000 units/g agarose (One ml gel will yield 12-30 units)
mol wt
~13,700
storage temp.
2-8°C
Physical form
Suspension in 2.0 M (NH4)2SO4 pH 7.0
Analysis Note
Electrophoretically and enzymatically assayed. RNase A and B contents determined by SDS-PAGE. Protein determined by E1%/280.
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
A spectrophotometric method for the measurement of ribonuclease activity.
M KUNITZ
The Journal of biological chemistry, 164(2), 563-568 (1946-08-01)
Chunju Li et al.
Journal of biotechnology, 162(2-3), 283-288 (2012-09-25)
Ribonuclease A (RNase A) is a therapeutic enzyme with cytotoxic action against tumor cells. Its clinical application is limited by the short half-life and insufficient stability. Conjugation of albumin can overcome the limitation, whereas dramatically decrease the enzymatic activity of
Marka van Blitterswijk et al.
PloS one, 7(11), e48983-e48983 (2012-11-17)
Progressive muscular atrophy (PMA) and amyotrophic lateral sclerosis (ALS) are devastating motor neuron diseases (MNDs), which result in muscle weakness and/or spasticity. We compared mutation frequencies in genes known to be associated with MNDs between patients with apparently sporadic PMA
Donald Gagné et al.
The Journal of biological chemistry, 287(53), 44289-44300 (2012-11-09)
Conformational flexibility between structural ensembles is an essential component of enzyme function. Although the broad dynamical landscape of proteins is known to promote a number of functional events on multiple time scales, it is yet unknown whether structural and functional
Shalini Iyer et al.
The FEBS journal, 280(1), 302-318 (2012-11-23)
Angiogenin (Ang) is a potent inducer of neovascularization. Point mutations in human Ang have been linked to cancer progression and two neurodegenerative diseases: amyotrophic lateral sclerosis and Parkinson's disease. Intensive structural and functional analyses of Ang have been paramount in
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service