All Photos(1)
Synonym(s):
(5aR-trans)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-amine dihydrochloride, LY-163,502
Empirical Formula (Hill Notation):
C14H22N4 · 2HCl
CAS Number:
Molecular Weight:
319.27
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Recommended Products
form
crystalline
color
white
solubility
H2O: >10 mg/mL
SMILES string
Cl.Cl.[H][C@]12CCCN(CCC)[C@]1([H])Cc3cnc(N)nc3C2
InChI
1S/C14H22N4.2ClH/c1-2-5-18-6-3-4-10-7-12-11(8-13(10)18)9-16-14(15)17-12;;/h9-10,13H,2-8H2,1H3,(H2,15,16,17);2*1H/t10-,13-;;/m1../s1
InChI key
WDEMLQIGYYLRRX-OWVUFADGSA-N
Gene Information
human ... DRD2(1813)
Biochem/physiol Actions
D2 dopamine receptor agonist; 2-aminopyridine analog of quinpirole.
Legal Information
Manufactured and sold with the permission of Eli Lilly and Company.
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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M J Eaton et al.
The Journal of pharmacology and experimental therapeutics, 268(2), 645-652 (1994-02-01)
The purpose of the present study was to characterize dopaminergic D2 receptor-mediated regulation of catecholaminergic neurons in the diencephalon by examining the acute effects of the potent and selective D2 agonist quinelorane (LY163502; trans-(-)-5,5a,6,7,8,9,9a,10-octahydro-6-propylpyrimido [4,5-g] quinolin-2-amine dihydrochloride dihydrate) on concentrations
M A Charles et al.
Pharmacology, biochemistry, and behavior, 43(4), 1087-1092 (1992-12-01)
LY163502, a selective D2 receptor agonist, has been reported to stimulate sexual behavior in both copulating and noncopulating male rats. Three experiments were conducted to further characterize the role of dopamine on male sexual behavior. In the first experiment, quinelorane
J H Carlson et al.
Synapse (New York, N.Y.), 11(3), 229-248 (1992-07-01)
The rates and patterns of discharge activity exhibited by 16 spontaneously active substantia nigra pars compacta dopamine neurons were studied in halothane-anesthetized rats using three types of quantitative measures: 1) mean discharge rates, 2) population characteristics of interspike interval samples
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