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PZ0359

Sigma-Aldrich

PF-06827443

≥98% (HPLC)

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Synonym(s):
2-((3R,4S)-3-Hydroxytetrahydro-pyran-4-yl)-5-methyl-6-(4-oxazol-4-yl-benzyl)-2,3-dihydro-isoindol-1-one
Empirical Formula (Hill Notation):
C24H24N2O4
CAS Number:
Molecular Weight:
404.46
UNSPSC Code:
12352200
NACRES:
NA.77

Quality Level

Assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 10 mg/mL, clear

storage temp.

room temp

SMILES string

CC1=CC(CN([C@@H]2[C@@H](O)COCC2)C3=O)=C3C=C1CC4=CC=C(C5=COC=N5)C=C4

Biochem/physiol Actions

PF-06827443 is a otent, low clearance, orally bioavailable, and CNS penetrant muscarinic M1-selectivepositive allosteric modulator (PAM) with minimal agonist activity.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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